Search for dissertations about: "plasminogen activator inhibitor"

Showing result 1 - 5 of 90 swedish dissertations containing the words plasminogen activator inhibitor.

  2. 1. Plasminogen : a pleiotropic inflammatory regulator in radiation-induced wound formation and wound repair

    Author : Mahsa Fallah; Tor Ny; Malgorzata Wilczynska; Robert Medcalf; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The plasminogen activator (PA) system plays important roles in many physiological and pathological processes, including inflammation and wound healing. Plasmin, the central component of the PA system, is a broad-spectrum serine protease that is derived from its inactive precursor form, plasminogen. READ MORE

  4. 2. Tissue-type plasminogen activator : molecular interactions with plasminogen activator inhibitor-1 and endothelial cell-surface proteins

    Author : Maria Ljung; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : .... READ MORE

  5. 3. Plasminogen activator inhibitor type-1 : structure-function studies and its use as a reference for intramolecular distance measurements

    Author : Peter Hägglöf; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomedicine; PAI-1 serpin RCL complex formation DDEM Intramolecular distance; Biomedicin; Microbiology; Mikrobiologi; medicinsk biokemi; Medical Biochemistry;

    Abstract : Inhibitors belonging to the serpin (serine protease inhibitor) family control proteases involved in various physiological processes. All serpins have a common tertiary structure based on the dominant b-sheet A, but they have different inhibitory specificity. READ MORE

  6. 4. Plasminogen activator inhibitor type 2 : a unique serpin with two mobile loops

    Author : Sergei Lobov; Umeå universitet; []
    Keywords : ;

    Abstract : The superfamily of serine protease inhibitors (serpins) is a large group of proteins with diverse functions but a common tertiary structure. Active serpins are highly metastable molecules. Metastability is the property underlying the success and ubiquitousness of serpins. READ MORE

  7. 5. Regional fluxes of tissue plasminogen activator in porcine endotoxemia

    Author : Annette Nyberg; Göteborgs universitet; []
    Keywords : pig; endotoxin; tissue type plasminogen activator; plasminogen activator inhibitor; tumor necrosis factor ?;

    Abstract : Formation of fibrin clots in the microcirculation during severe sepsis contributes to organ failure, frequently involving the lungs and the splanchnic organs. Tissue type plasminogen activator, tPA, is the key activator of intravascular fibrinolysis with plasminogen activator inhibitor type-1, PAI-1, as its main inhibitor. READ MORE