Search for dissertations about: "platelet-derived growth factor receptor"
Showing result 1 - 5 of 95 swedish dissertations containing the words platelet-derived growth factor receptor.
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1. Functions of platelet-derived growth factor-A during organogenesis
Abstract : The formation of organs during embryonic development is calledorganogenesis. This process is regulated by the genes residing in the genome. READ MORE
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2. Platelet-derived growth factor-induced signal transduction
Abstract : Platelet-derived growth factor (PDGF), a potent mitogen for mesenchymal cells, elicits its effects by binding to cell surface tyrosine kinase receptors, denoted α- and β-receptors. This thesis describes the mechanism of interaction between stimulated PDGF receptors and various intracellular molecules. READ MORE
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3. Regulation of the platelet-derived growth factor β-receptor
Abstract : Growth factors are important signalling molecules, regulating cell growth, as well as cell movement, differentiation and apoptosis. They bind to specific receptors on the cell surface causing activation of the receptors. Activated receptors then attract adaptor molecules that brings the signal further into the cell. READ MORE
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4. Pericyte recruitment and functions in vivo. Studies of platelet-derived growth factor-B deficient embryos
Abstract : A functional vascular system is essential for tissue growth and maintenance, and the circulatory system is therefore the first operational organ of the vertebrate embryo. In conditions of pathological tissue growth, such as tumors, formation of new blood vessels is also required, and it is anticipated that prevention of blood vessel development in those settings might ameliorate the disease progress. READ MORE
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5. Transcriptional Regulation of the Platelet-Derived Growth Factor beta-receptor
Abstract : The Platelet Derived-Growth Factor (PDGF) receptors and ligands are expressed in cells of predominantly mesenchymal origin. Binding of the ligands to the receptors stimulates cell proliferation and other cellular responses such as differentiation and cell movement. READ MORE