Search for dissertations about: "porphyrin metallation"

Found 5 swedish dissertations containing the words porphyrin metallation.

  2. 1. Crystallographic studies on porphyrin metallation by ferrochelatase

    Author : David Lecerof; Biokemi och Strukturbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; thermal and mechanical properties; Condensed matter:stucture; fasjämvikt; kristallografi; egenskaper termiska och mekaniska ; Kondenserade materiens egenskaper:struktur; crystallography; phase equilibria; Magnesium; pi-helix; Zinc; ferrochelatase; Metal binding; porphyrin metallation;

    Abstract : Ferrochelatase catalyses the terminal step in heme biosynthesis by inserting a ferrous ion into protoporphyrin IX. The reaction mechanism has in this thesis been studied by mainly crystallographic methods. READ MORE

  4. 2. Structural and physicochemical studies on metal and porphyrin binding by the Bacillus subtilis ferrochelatase

    Author : Mattias Hansson; Biokemi och Strukturbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; metal specificity; metal binding; porphyrin metallation; time resolved crystallography; fluorescence quenching; X-ray structure; inclusion bodies; Bacillus subtilis; heme biosynthesis; ferrochelatase; hemH;

    Abstract : The enzyme ferrochelatase (EC 4.99.1.1) is the terminal enzyme in the biosynthetic pathway of heme b and catalyzes the insertion of Fe(II) into protoporphyrin IX. READ MORE

  5. 3. Enzymatic metal-chelation by porphyrins

    Author : Andreas Hansson; Biokemi och Strukturbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; tetrapyrrole; Plant biochemistry; Växtbiokemi; MIDAS; metallation; magnesium chelatase; integrin; heme; ferrochelatase; chlorophyll; barley; AAA ; ATPase;

    Abstract : This thesis deals with the structure and function of two different enzymes, ferrochelatase and magnesium chelatase, that catalyse similar reactions. When this work started, a three-dimensional model of ferrochelatase existed. Much was known about the enzyme, but some details remained unclear. READ MORE

  6. 4. Structure and mechanism of iron and magnesium chelatases - at the heme-chlorophyll branch-point

    Author : Michel Fodje; Lunds universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biophysics; pi-helix; secondary structure; AAA; porphyrin metallation; chelatase; Molekylär biofysik;

    Abstract : Tetrapyrroles are synthesised through a single branched biosynthetic pathway. Heme and chlorophyll are synthesised from the common intermediate protoporphyrin IX at the heme-chlorophyll branch-point. READ MORE

  7. 5. Iron in Haem Biosynthesis. Structural Studies of Ferrochelatase and Frataxin

    Author : Tobias Karlberg; Biokemi och Strukturbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Naturvetenskap; Natural science; Molekylär biofysik; Molecular biophysics; Biomedicinska vetenskaper; Biomedical sciences; protein crystallography; ferrochelatase; haem biosynthesis; iron; frataxin;

    Abstract : Ferrochelatase catalyses the synthesis of heme by inserting Fe(II) into protoporphyrin IX. The structure of ferrochelatase from yeast has been determined (2.4 Å). The structure is homodimeric with each of the monomer made up of two Rossmann type domains with an active-site cleft between them. READ MORE