Search for dissertations about: "post-mortem brain"

Showing result 1 - 5 of 71 swedish dissertations containing the words post-mortem brain.

  2. 1. Post mortem studies on the human alcoholic brain : DNA methylation and molecular responses

    Author : Sofia Johansson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Chronic alcoholism is a multi-factorial psychiatric disease manifested by re-occurring periods of relapse with frequent symptoms of cognitive impairments. There is no explanation to the extreme vulnerability to relapse, since this often occurs without evident molecular or biochemical changes remaining at the time of relapse. READ MORE

  4. 2. Synaptic plasticity in drug abuse disorders : studies of the human post-mortem brain

    Author : Anna Ökvist; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Drug addiction is a chronic disorder characterized by craving and compulsive drug use despite adverse consequences and high rates of relapse during periods of abstinence. Therapeutic interventions for most addiction disorders are limited today, partly because the underlying neurobiology is still unknown. READ MORE

  5. 3. MRI Studies of the Fetal Brain and Cranium

    Author : Nuno Canto Moreira; Johan Wikström; Raii Raininko; Daniela Prayer; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fetal MRI; Brain; Cranium; Development; Normal; Ear; Lip; Palate; Biometry; Hippocampus; Measurements; Radiologi; Radiology;

    Abstract : Ultrasound is the primary modality for fetal imaging, but Magnetic Resonance Imaging nowadays has a valuable complementary role as it often reveals findings that alter pregnancy management. Knowledge on some clinically relevant areas of the normal fetal development is still lacking, and this was the aim of this project. READ MORE

  6. 4. High-resolution Studies of mRNA Expression in Brain : A Search for Genes Differently Expressed in Schizophrenia

    Author : Anja Castensson; Elena Jazin; Terence Speed; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; mRNA; gene expression; real-time RT-PCR; schizophrenia; 5-HT serotonin receptor 2C; brain; psychiatric genetics; Genetik; Clinical genetics; Klinisk genetik;

    Abstract : Gene expression differences between patients and controls can be used to find susceptibility genes and drug targets for a disease. High-resolution strategies are required because the differences between the investigated groups may be small and numerous factors may affect the mRNA quantity. READ MORE

  7. 5. Characterization of immune cell profiles in meninges and brain parenchyma following injury in the developing mouse brain

    Author : Aura Zelco; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; preterm brain injury; hypoxia-ischemia; immune response; neonatal meninges;

    Abstract : Preterm newborns are particularly susceptible to complications such as hypoxia-ischemia (HI), which can result in brain injury and subsequent cognitive and/or motor function disabilities, including cerebral palsy. Immune cells have been shown to be involved in the development of perinatal brain damage, commonly with detrimental effects. READ MORE