Search for dissertations about: "potassium channel"

Showing result 1 - 5 of 70 swedish dissertations containing the words potassium channel.

  1. 1. Signal transduction in the brain modulation of receptor-mediated inositol phospholipid breakdown by potassium and fluoride ions

    University dissertation from Umeå : Umeå universitet

    Author : Gunnar Tiger; Umeå universitet.; [1990]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Inositol phospholipid breakdown; muscarinic receptors; potassium; fluoride; rat brain; pig brain;

    Abstract : Neurotransmitter receptor types mediating the generation of intracellular signals are of two types; ligand-gated ion channels and G protein coupled receptors. The effector enzyme phosphoinositide-specific phospholipase C (PLC) is modulated by stimulation of G protein coupled receptors, leading to an increased breakdown of inositol phospholipids ("Ptdlns breakdown"). READ MORE

  2. 2. A study of potassium channel activation as a pharmacological principle for vasodilation of cerebral blood vessels

    University dissertation from Department of Clinical Pharmacology, Lund University Hospital

    Author : Torsten Ryman; Lunds universitet.; Lund University.; [1999]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacological sciences; cerebral arteries; Cerebral ischemia; Potassium channel openers; vascular endothelium; EDHF; KRN2391; KATP; Pinacidil; pharmacognosy; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi;

    Abstract : Popular Abstract in Swedish Stroke är en heterogen sjukdom som inkluderar främst hjärninfarkt samt hjärn- och hjärnhinneblödningar från sprucken pulsåderbråck. Stroke är den tredje största dödsorsaken i industriländerna efter hjärtinfarkt och cancer. Varje år drabbas t.ex. READ MORE

  3. 3. Pulsatile insulin release from single islets of Langerhans

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Johanna Westerlund; Uppsala universitet.; [2000]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; islets of Langerhans; insulin; ELISA; cytoplasmic calcium; oscillations; type 2 diabetes; glucose; diazoxide; potassium; tolbutamide; DNP; antimycin A; iodoacetamide; microfluorometry; fura-2; KATP channels; Cellbiologi; MEDICINE Morphology; cell biology; pathology Cell biology; MEDICIN Morfologi; cellbiologi; patologi Cellbiologi; Medical Cell Biology; medicinsk cellbiologi;

    Abstract : Insulin release from single islets of Langerhans is pulsatile. The secretory activities of the islets in the pancreas are coordinated resulting in plasma insulin oscillations. Nutrients amplitude-regulate the insulin pulses without influencing their frequency. READ MORE

  4. 4. Structural and functional studies of biomolecules with NMR and CD spectroscopy

    University dissertation from Stockholm : Institutionen för biokemi och biofysik

    Author : Evangelos Papadopoulos; Stockholms universitet.; [2008]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NMR; protein structure; nouse Doppel; HTH; C-repressor; potassium channel; TECHNOLOGY Engineering physics Biophysics; TEKNIKVETENSKAP Teknisk fysik Biofysik; Biophysics; biofysik;

    Abstract : Experimentally derived biomolecular structures were determined by Nuclear Magnetic Resonance (NMR). The properties of selected peptides and proteins in solution and in membrane mimicking micelles were observed by circular Dichroism (CD), mass spectrometry (MS), and other spectroscopic techniques. READ MORE

  5. 5. A-type Potassium Channels in Dendritic Integration Role in Epileptogenesis

    University dissertation from Stockholm : KTH Royal Institute of Technology

    Author : Jenny Tigerholm; KTH.; [2009]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; epileptogenesis; fast ripples; synchronicity; dendritic potentials; transient A–type potassium current; KV 4.2; SOCIAL SCIENCES Statistics; computer and systems science Informatics; computer and systems science Computer and systems science; SAMHÄLLSVETENSKAP Statistik; data- och systemvetenskap Informatik; data- och systemvetenskap Data- och systemvetenskap;

    Abstract : During cognitive tasks, synchronicity of neural activity varies and is correlated with performance. However, there may be an upper limit to normal synchronised activity – specifically, epileptogenic activity is characterized byexcess spiking at high synchronicity. READ MORE