Search for dissertations about: "pre clinical cancer thesis"

Showing result 1 - 5 of 198 swedish dissertations containing the words pre clinical cancer thesis.

  2. 1. Translational and clinical aspects of pancreatic cancer

    Author : Caroline Vilhav; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pancreatic cancer; circulating tumor cells; extracellular vesicles; immunotherapy; PDX model; pancreaticoduodenectomy; postoperative complications; postpancreatectomy hemorrhage;

    Abstract : Pancreatic cancer is a disease with dismal prognosis due to late detection and ineffective treatments. The majority of the patients already have disseminated disease at the time of diagnosis. The only potential curative treatment, surgery, is extensive with high morbidity and non-ignorable mortality. READ MORE

  4. 2. Rectal Cancer - Tumor Biology and Prognostic Markers

    Author : Eva Fernebro; Bröstcancer-genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prognostic markers; Cytology; oncology; cancerology; Cytologi; onkologi; cancer; immunohistochemistry IHC ; chromosomal instability CIN ; microsatellite instability MSI ; tissue microarray TMA ; tissue inhibitor of metalloproteinase 1 TIMP-1 ; Rectal cancer; soluble urokinase plasminogen activator receptor suPAR ;

    Abstract : Colorectal cancer is one of our most common malignancies and the second leading cause of cancer death worldwide. About 1/3 of the tumors are located in the rectum. READ MORE

  5. 3. The breast cancer microenvironment and cancer cell secretion - specific effects on cancer progression and subtypes of cancer cells

    Author : Emma Persson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; cancer microenvironment; secretion; hypoxia;

    Abstract : Breast cancer is the cancer form responsible for the most cancer-related deaths among women worldwide, and novel targeted therapies are highly needed. The tumor microenvironment consists of several components, including different cell types, extracellular matrix, oxygen and nutrient gradients and soluble factors that plays a key role in cancer progression. READ MORE

  6. 4. Prostanoids and colorectal cancer

    Author : Annika Gustafsson Asting; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colorectal cancer prostanoid receptors cyclooxygenase PGE2 transcription factors;

    Abstract : Tumor disease is a main cause of death in Western countries and a most common malignancy is colorectal cancer (CRC). Growing tumors are dependent on interactions among several different cells as well as signaling pathways. READ MORE

  7. 5. Rectal cancer : Aspects of post-operative complications

    Author : Ingvar Sverrisson; Kennet Smedh; Maziar Nikberg; Abbas Chabok; Anna Martling; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rectal cancer; Complications; Anastomotic leakage; Abscess; Parastomal hernia; Prostate cancer; Radiation therapy; Surgery; Kirurgi;

    Abstract : Aim: The overall aim of this thesis was to study post-operative complications in patients with rectal cancer.Methods: Post-operative complications in patients operated for rectal cancer was retrospectively analyzed in three prospective registers; the local rectal cancer registry in the Västmanland County, Sweden, the Swedish Colorectal Cancer Registry (SCRCR) and the National Prostate Cancer Registry (NPCR). READ MORE