Search for dissertations about: "pre clinical"

Showing result 1 - 5 of 1061 swedish dissertations containing the words pre clinical.

2. 1. Aspects of the Pre-Diabetic Period in Type 1 Diabetes

   Author : Linda Åkerman; Rosaura Casas; Johnny Ludvigsson; Susan Wong; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

   Abstract : Type 1 diabetes (T1D) is an autoimmune disease characterized by insulin deficiency, due to immune-mediated destruction of beta cells. Current knowledge regarding the period preceding disease onset comes, to a large extent, from studying risk cohorts based on relatives of T1D-patients, as they have an increased disease risk. READ MORE

4. 2. Insomnia Symptoms in Chronic Pain : Clinical presentation, risk and treatment

   Author : Tobias Wiklund; Elena Dragioti; Steven J. Linton; Björn Gerdle; Péter Alföldi; Bjørn Bjorvatn; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Abstract : In recent years, chronic and recurrent pain have gained interest as distinct conditions interacting both with peripheral and central parts of the nervous system as well as with the immune system. The risk of getting affected by abnormal pain modulation i.e. READ MORE

5. 3. Nuclear medicine methods in idiopathic Parkinsonism : pre- and postsynaptic dopamine SPECT

   Author : Susanna Jakobson Mo; Katrine Åhlström Riklund; Anne Larsson Strömvall; Lars Forsgren; Rimma Axelsson; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nuclear medicine; SPECT; 123I-FP-Cit; 123I-IBZM; dopamine; parkinsonism; Parkinson’s disease; multiple system atrophy; progressive supranuclear palsy; Radiology; radiologi;

   Abstract : Background: Single photon emission computed tomography (SPECT) with dopamine transporter (DAT) and dopamine D2 receptor (D2R) ligands can visualise the integrity of the nigrostriatal dopamine system. Parkinson’s disease (PD) and the atypical parkinsonian diseases (APD), progressive supranuclear palsy (PSP) and multiple system atrophy (MSA), have similar symptoms and dopamine depletion, but differ in pharmacological response and prognosis. READ MORE

6. 4. Chronic obstructive pulmonary disease : clinical phenotyping, mortality and causes of death

   Author : Sami Sawalha; Anne Lindberg; Helena Backman; Nikolai Stenfors; Karin Lisspers; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Phenotyping; chronic airflow obstruction; COPD; productive cough; pre- and postbronchodilator airway obstruction; co-morbidity; epidemiology; mortality; causes of death; sex; lungmedicin; Lung Medicine;

   Abstract : Background: Chronic obstructive pulmonary disease (COPD) is common. The estimated prevalence is about 10% among adults, but varies largely dependent on the major risk factors age and smoking. Under-diagnosis of COPD is substantial and is related to disease severity. READ MORE

7. 5. Development and Evaluation of a Computerised Decision Support System for use in pre-hospital care

   Author : Magnus Hagiwara; Björn-Ove Suserud; Eldar Søreide; Jönköping University; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prehospital care; patient assessment; clinical judgment; decision making; patient safety; human error; decision support;

   Abstract : The aim of the thesis was to develop and evaluate a Computerised Decision Support System (CDSS) for use in pre-hospital care.The thesis was guided by a theoretical framework for developing and evaluating a complex intervention. The four studies used different designs and methods. READ MORE