Search for dissertations about: "pre-mRNA processing"

Showing result 1 - 5 of 18 swedish dissertations containing the words pre-mRNA processing.

  2. 1. The SWI/SNF complex : Roles in transcription and pre-mRNA processing

    Author : Johan Waldholm; Neus Visa; Ann-Kristin Östlund; Silvia Barabino; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Splicing; Gene regulation; SWI SNF; polyadenylation; Molecular Biology; molekylärbiologi;

    Abstract : The regulation of gene expression is fundamental to the development of complex organisms and an important driving force in this process. When and where the genes are expressed decide the fate of a cell and its physiological context in the organism. READ MORE

  4. 2. Biochemical and structural studies of pre-mRNA splicing

    Author : Ingela Wetterberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Gene expression; pre-mRNA processing; transcription; in situ; electron tomography;

    Abstract : When eucaryotic genes are expressed, they are transcribed into pre-mRNAs (precursor mRNAs) that need extensive processing before they can be exported from the nucleus as mRNAs and translated into proteins in the cytoplasm. One central processing event is splicing, which means removal of intervening, non-coding sequences, introns and joining of functional sequences, exons. READ MORE

  5. 3. Pre-mRNA processing in the polytene nuclei of chironomus tentans

    Author : Göran Baurén; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Pre-mRNA processing; Organization of splicing factors; Cotranscriptionalsplicing; Transcription termination; Chironomus tentans; Polytene nuclei.;

    Abstract : Gene expression of protein encoding genes in eukaryotic cells requires extensive intranuclear maturation processing of the transcribed pre-mRNA. Three such processes are known to occur. The 5' end is capped and the 3' end is determined by cleavage and polyadenylation. READ MORE

  6. 4. ATPase dependent and independent roles of Brahma in transcription and pre-mRNA processing

    Author : Simei Yu; Neus Visa; Ann-Kristin Östlund Farrants; Christian Muchardt; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; chromatin remodeling; transcription; alternative splicing; 3 -end processing; Molecular Biology; molekylärbiologi;

    Abstract : SWI/SNF is a chromatin-remodeling complex and Brahma (BRM) is the ATPase subunit of SWI/SNF. BRM regulates transcription by remodeling the nucleosomes at promoter regions. BRM is also associated with RNA and affects pre-mRNA processing together with other SWI/SNF subunits. READ MORE

  7. 5. Molecular Cloning and Functional Characterization of Factors Involved in Post-transcriptional Gene Expression

    Author : Shao-Bo Jin; Lars Wieslander; Maria Carmo-Fonseca; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; gene expression; pre-mRNA processing; pre-rRNA processing; Molecular biology; Molekylärbiologi;

    Abstract : Gene expression in the eukaryotic cell is a fundamental cellular process, which consists of several distinct steps but extensively coupled to each other. From site of transcription in the nucleus to the cytoplasm, both mRNA and rRNA are associated with a proper set of proteins. READ MORE