Search for dissertations about: "pre-rRNA processing"

Found 5 swedish dissertations containing the words pre-rRNA processing.

  2. 1. Molecular Cloning and Functional Characterization of Factors Involved in Post-transcriptional Gene Expression

    Author : Shao-Bo Jin; Lars Wieslander; Maria Carmo-Fonseca; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; gene expression; pre-mRNA processing; pre-rRNA processing; Molecular biology; Molekylärbiologi;

    Abstract : Gene expression in the eukaryotic cell is a fundamental cellular process, which consists of several distinct steps but extensively coupled to each other. From site of transcription in the nucleus to the cytoplasm, both mRNA and rRNA are associated with a proper set of proteins. READ MORE

  4. 2. Eukaryotic Ribosome Biogenesis : Focus on the function of the assembly factor Mrd1p

    Author : Åsa Segerstolpe; Lars Wieslander; Susan Gerbi; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Ribosome biogenesis; nucleolus; pre-rRNA processing; RNA-binding proteins; Mrd1; Molecular Biology; molekylärbiologi;

    Abstract : The ribosome, the protein factory of the cell, is essential for all life forms. The ribosome is a large RNA-protein machine. It is built in a complex, multi-step process that involves a large number of accessory trans-acting factors and the synthesis consumes a considerable part of the cellular energy. READ MORE

  5. 3. Nucleolar Ribosome Assembly

    Author : Fredrik Lackmann; Lars Wieslander; Denis Lafontaine; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Ribosome biogenesis; RNA; Nucleolus; Molecular Biology; molekylärbiologi;

    Abstract : Ribosomes are macromolecular machines that are responsible for production of every protein in a living cell. Yet we do not know the details about how these machines are formed. The ribosome consists of four RNA strands and roughly 80 proteins that associate with each other in the nucleolus and form pre-ribosomal complexes. READ MORE

  6. 4. Biogenesis of messenger and ribosomal RNPs in the eukaryotic cell

    Author : Petra Björk; Juan Valcárcel; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Molekylärbiologi; Physical Biology; fysikalisk biologi;

    Abstract : In eukaryotic cells, gene expression involves multi-step processes in the nucleus and the cytoplasm. The different processes engage specific RNA-protein complexes, RNPs. Upon activation of most, if not all genes, a precursor RNA molecule is synthesized that has to be extensively processed and modified. READ MORE

  7. 5. mRNA degradation factors as regulators of the gene expression in Saccharomyces cerevisiae

    Author : Mridula Muppavarapu; Tracy Nissan; Per Sunnerhagen; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mRNA decapping; mRNA degradation; Pat1; Edc3; Lsm4; Lsm1-7; P bodies; Dcp2; Transcription; Ribosome biogenesis; Exosome.; molekylärbiologi; Molecular Biology;

    Abstract : Messenger RNA degradation is crucial for the regulation of eukaryotic gene expression. It not only modulates the basal mRNA levels but also functions as a quality control system, thereby controlling the availability of mRNA for protein synthesis. READ MORE