Search for dissertations about: "preclinical Alzheimer s disease"

Found 3 swedish dissertations containing the words preclinical Alzheimer s disease.

2. 1. Methods to study glymphatic system in the rodent brain during physiological and pathological processes

   Author : Roberta Battistella; Glia-Immune Interactions; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glymphatic system; Aquaporin-4; Lectins; Parkinson´s disease; α-synuclein; Hypothermia;

   Abstract : Over the past decade, our understanding of brain-waste clearance underwent a revolution after the discovery of the so-called glymphatic system. The glia-lymphatic (abbreviated, glymphatic) system was first described in 2012 as a paravascular macrosystem involved in the distribution of nutrients and clearance of metabolic waste from the brain parenchyma. READ MORE

4. 2. Memory, genes, and brain imaging : relating the APOE gene to brain function and structure

   Author : Johanna Lind; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Alzheimer´s disease (AD) is the most common form of dementia. An important goal for current AD research is to find preclinical markers of impending disease. Apolipoprotein E sigma4 (APOE epsilon4) is the chief known genetic risk factor for AD. READ MORE

5. 3. Predictors of cognitive decline in memory clinic patients

   Author : Christin Andersson; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Background: The major challenge in memory clinics is to predict development as well as non-development of dementia among the heterogeneous group of patients with cognitive complaints. Since the advent of pharmacological treatment possibilities for patients with Alzheimer s disease (AD), much research has been focused on predictors for dementia since initiation of treatment in the preclinical phase may prevent development of dementia. READ MORE