Search for dissertations about: "preclinical"
Showing result 1 - 5 of 311 swedish dissertations containing the word preclinical.
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1. EGFR and HER2 Targeting for Radionuclide-Based Imaging and Therapy : Preclinical Studies
Abstract : The optimal way to detect and treat cancer is to target cancer cells exclusively without affecting the surrounding tissue. One promising approach is to use radiolabelled molecules to target receptors that are overexpressed in cancer cells. READ MORE
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2. Antibody Mediated Radionuclide Targeting of HER-2 for Cancer Diagnostics and Therapy : Preclinical Studies
Abstract : Targeted radionuclide therapy (TRT) holds great promise for the treatment of cancer. In TRT, radioactive nuclides are delivered specifically to tumours by molecules that recognise and bind to structures overexpressed by, or specific to, cancer cells. READ MORE
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3. Radioimmunodiagnosis of Head and Neck Squamous Cell Carcinomas : Preclinical Studies
Abstract : Despite improvements in treatment, the prognosis for patients with advanced head and neck squamous cell carcinomas (HNSCC) has only improved to a minor degree. To raise the success rate and minimize morbidity further developments in diagnostics are highly desired. Radioimmunodiagnosis could offer a more specific and sensitive diagnostic method. READ MORE
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4. Radiolabeled HER-2 Binding Affibody Molecules for Tumor Targeting : Preclinical Studies
Abstract : Conventional cancer treatment based on radiotherapy or chemotherapy affects all dividing cells. By directing the therapy specifically to the tumor cells, normal cells can be spared. Tumor targeting molecules carrying a cytotoxic moiety is then an attractive approach. READ MORE
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5. Tumour Targeting Using Radiolabelled EGF Conjugates : Preclinical Studies
Abstract : Tumour targeted radiotherapy is an appealing approach for treatment of disseminated tumour cells. A targeting agent that specifically binds to a structure on tumour cells is then used to transport therapeutically relevant radionuclides. The epidermal growth factor receptor, EGFR, is overexpressed on tumour cells in several malignancies, e.g. READ MORE