Search for dissertations about: "precursor cells"
Showing result 1 - 5 of 298 swedish dissertations containing the words precursor cells.
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1. Regulatory Proteins in Progenitors and Differentiated Cells of the Human Prostate
Abstract : Prostate cancer (PC) develops from an androgen-dependent tissue that contains androgen receptors in both the stromal and glandular compartments. Surgical removal of the prostate may cure the patient, but if metastatic spread has occurred, androgen suppression therapy is the standard treatment. READ MORE
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2. Assessment of precursor cell proliferation in normal and injured adult mammalian brains
Abstract : In the adult mammalian brain, new neurons are generated from neural stem cells (NSCs) which reside in the subventricular zone (SVZ) of the lateral ventricle wall and in the subgranular zone (SGZ) of the dentate gyrus (DG) in the hippocampus. The biology of persistent NSCs in the adult brain is poorly understood. READ MORE
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3. Interactions between mouse CNS cells : microglia and neural precursor cells
Abstract : The mammalian central nervous system (CNS) contains a variety of cells, all specialized to perform different functions. Most numerous are the three types of glia cells, whose basic role is to support the signaling units of the CNS, the neurons. READ MORE
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4. Molecular specification of expanded forebrain neural stem and progenitor cells
Abstract : The molecular specification of neural precursor cells has been suggested to be a progressive process, with a transition from an early requirement for extrinsic signals to intrinsic mechanisms. Thus, the cells in the nervous system acquire distinct fates in response to extrinsic signals, which activate repertoires of transcription factors in a region and cell type specific manner. READ MORE
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5. Regulatory properties of dendritic cells and B cells in adaptive immunity
Abstract : This thesis is based upon four original papers in which human dendritic cells (DCs) and B cells have been analyzed in terms of how they influence the character of adaptive immune responses. DCs isolated from human tonsils were found to possess a capacity to directly regulate proliferation, isotype switching, and antibody production in B cells. READ MORE