Search for dissertations about: "prognostic marker"

Showing result 21 - 25 of 245 swedish dissertations containing the words prognostic marker.

  2. 21. Prognostic factors in soft tissue sarcoma. Tissue microarray for immunostaining, the importance of whole-tumor sections and time-dependence

    Author : Jacob Engellau; Bröstcancer-genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; growth pattern; time-dependence; P-glycoprotein Pgp ; CD44; β-catenin; cyclin A; bcl-2; p53; Ki-67; immunohistochemistry IHC ; whole-tumor sections; tissue microarray TMA ; Soft tissue sarcoma; prognostic factors; Cytology; oncology; cancerology; Cytologi; onkologi; cancer;

    Abstract : In adult soft tissue sarcoma (STS) of the extremities and trunk wall, improved prognostic factors are needed to identify patients at high-risk for metastasis. Various factors are included in the many prognostic systems currently in use and the prognostic value of immunohistochemical (IHC) expression of biological markers is unclear. READ MORE

  4. 22. Sarcoma ecosystems : spatial characterization and prognostic significance

    Author : Yanhong Su; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Sarcoma is a highly heterogeneous disease with complex biological activities and unique tumor microenvironments (TME) in distinct subtypes. The limited treatment options and inadequate responses to current therapies necessitate a deeper understanding of sarcoma biology and personalized treatment strategies. READ MORE

  5. 23. Prognostic and predictive factors in colorectal cancer

    Author : Kristoffer Derwinger; Göteborgs universitet; []
    Keywords : colorectal cancer; prognosis; lymph nodes; lymph node ratio; MTHFR; cyclin E; TNM; staging; metastasis;

    Abstract : Aim: The aim of the thesis was to study prognostic and predictive factors in patients treated for colorectal cancer (CRC). Method: In paper I, a retrospective comparison was made between the patients treated in 1999 (n=180) with those treated in 2004 (n=175). READ MORE

  6. 24. The role of RNA-binding motif 3 in epithelial ovarian cancer: A biomarker discovery approach

    Author : Åsa Ehlén; Malmö Patologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; DNA integrity checkpoint; cisplatin treatment; prognostic predictive marker; RBM3; epithelial ovarian cancer; Chk1; Chk2; MCM3;

    Abstract : Epithelial ovarian cancer (EOC) is the most lethal of all gynaecological malignancies and there is an urgent need to develop new prognostic and treatment predictive biomarkers for a more efficient therapy. The discovery of the RNA-binding motif protein 3 (RBM3) as a putative cancer biomarker was based on its differential expression in various cancer forms in the Human Protein Atlas (HPA). READ MORE

  7. 25. Colorectal Cancer - Evaluation of MMP as a prognostic marker and a model for peritoneal response

    Author : Andreas Jonsson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Colorectal neoplasms; matrix metalloproteinases; colorectal surgery; survival; prognosis; peritoneum; peritoneal neoplasms;

    Abstract : Background : There are about 6600 patients diagnosed with colorectal cancer in Sweden each year. Survival rates vary with cancer stage at diagnosis. The main treatment is surgery together with, in some cases, oncological treatment. Matrix metalloproteinases (MMP) are deeply involved in the growth and spread of colorectal cancer tumours. READ MORE