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Found 3 swedish dissertations matching the above criteria.

  2. 1. Prolactin receptor expression and prolactin-mediated effects in adipose tissue

    Author : Charlotte Ling; Göteborgs universitet; []
    Keywords : adipose tissue; prolactin receptor; SOCS; leptin; resistin; lipoprotein lipase;

    Abstract : The aim of this study was to investigate the presence of functional prolactin receptors (PRLRs) in white adipose tissue of mice and humans, and the possible functions mediated via PRLRs. In mouse white adipose tissue, three PRLR mRNA isoforms, L-, S2-, and S3-PRLR, and L-PRLR protein expression were detected. READ MORE

  4. 2. Effects of prolactin on metabolism - changes induced by hyperprolactinemia

    Author : Louise Nilsson; Göteborgs universitet; []
    Keywords : prolactin; prolactin receptor; hyperprolactinemia; adipose tissue; lipoprotein lipase; malonyl-CoA; glucose transporter 4; retinol-binding protein 4; adiponectin; lipid oxidation;

    Abstract : High prolactin levels during breast-feeding, is recognized to influence metabolism in order to supply glucose and fat for milk production. Pathologic overproduction of prolactin, hyperprolactinemia, is a condition primarily associated with reproductive disorders; however, the metabolic impact of elevated prolactin indicates that these parameters might be considered in clinical management of the condition. READ MORE

  5. 3. Receptors for growth hormone and prolactin. Regulation and activation

    Author : Gunnel Hellgren; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Growth hormone; GH receptor; Janus kinase; GH sensitivity; 5 -untranslated region; prolactin; prolactin receptor adipose tissue; liver; skeletal muscle; epidermal growth factor receptor; tyrosine kinase; kinase activity;

    Abstract : Cytokine receptor activation is dependent on ligand-induced receptor dimerization or oligomerization and subsequent activation of several intracellular proteins. Activation of Janus kinases (Jaks) is probably the first intracellular event that occurs after receptor dimerization. READ MORE