Search for dissertations about: "prostaglandin E"

Showing result 1 - 5 of 66 swedish dissertations containing the words prostaglandin E.

  2. 1. Studies of prostaglandin E2 formationin human monocytes

    Author : Sofia Karlsson; Jonny Wijkander; Christina Gustafson-Svärd; Karlstads universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prostaglandin E2; arachidonic acid; phospholipase A2; cyclooxygenase; prostaglandin E synthase; human monocytes; Medical cell biology; Medicinsk cellbiologi; Biomedical Sciences; Biomedicinsk vetenskap;

    Abstract : Prostaglandin (PG) E2 is an eicosanoid derived from the polyunsaturated twenty carbon fatty acid arachidonic acid (AA). PGE2 has physiological as well as pathophysiological functions and is known to be a key mediator of inflammatory responses. READ MORE

  4. 2. Prostaglandin E2 in Brain-mediated Illness Responses

    Author : Louise Elander; Anders Blomqvist; Marianne Schultzberg; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prostaglandin e2; PGE2; cox-1; cox-2; mPGES-1; fever; anorexia; food intake; HPA-axis; EP-receptor; LPS; IL-1; IL-6; MEDICINE; MEDICIN; Neurobiology; Neurobiologi;

    Abstract : We are unceasingly exposed to potentially harmful microorganisms. The battle against threatening infectious agents includes activation of both the innate and of the adaptive immune systems. READ MORE

  5. 3. Structure and function of microsomal prostaglandin E synthase-1

    Author : Sven-Christian Pawelzik; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The glutathione-dependent enzyme microsomal prostaglandin E synthase-1 (MPGES1) plays a pivotal role in inflammatory diseases. MPGES1 is up-regulated by pro-inflammatory cytokines in concert with cyclooxygenase (COX) -2, and the concerted action of both enzymes leads to the production of induced prostaglandin E2 (PGE2), a potent lipid mediator of inflammation, pain, and fever. READ MORE

  6. 4. Novel therapy for neuroblastoma : focus on prostaglandin E2 and microsomal prostaglandin E synthases-1

    Author : Anna Kock; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Cancer is a major public health problem and to date cancer is one of the leading causes of death worldwide. Neuroblastoma is a malignant pediatric tumor of the sympathetic nervous system. Neuroblastoma is one of the most common and deadliest extra cranial tumors of childhood. READ MORE

  7. 5. Three - dimensional ultrasound studies of the cervix in pregnancy

    Author : Linas Rovas; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; andrology; gynaecology; Obstetrics; Prostaglandin .; Labor induction .; Spontaneous delivery .; Pregnancy .; Cervix uteri .; Blood flow indices .; Doppler ultrasound .; Three-dimensional imaging .; sexuality; reproduction; Obstetrik; sexualitet; reproduktion; gynekologi; andrologi;

    Abstract : The aim of this thesis was to evaluate cervical physiological changes by three-dimensional (3D) ultrasound during pregnancy and to investigate the ability of 3D power Doppler to predict time to spontaneous and induced delivery in prolonged pregnancy. The thesis is based on five studies: reproducibility of cervical measurements by 3D power Doppler ultrasound (study I), reference data representative normal findings of the cervix assessed by 3D ultrasound during pregnancy (studies II, III) and the ability of 3D power Doppler to predict time to spontaneous and induced delivery in prolonged pregnancy. READ MORE