Search for dissertations about: "protein delivery"

Showing result 1 - 5 of 262 swedish dissertations containing the words protein delivery.

2. 1. Recombinant subunit vaccines : protein immunogens

   Author : Sissela Liljeqvist; KTH; []
   Keywords : ;

   Abstract : Recombinant techniques provide valuable tools for thedevelopment of modern subunit vaccines. In this thesisdifferent systems for production of recombinant subunitvaccines are presented. The strategies investigated includeprotein immunogens, live bacterial vectors and nucleicacids. READ MORE

4. 2. Tailoring of Biomaterials using Ionic Interactions : Synthesis, Characterization and Application

   Author : Björn Atthoff; Jöns Hilborn; Tim Bowden; Mats Andersson; Uppsala universitet; []
   Keywords : Chemistry; biodegradable polymers; ionomer; water uptake; protein delivery; protein adsorption; protein membrane; cell seeding efficiency; amphiphillic; inner structure; polarized membrane; Kemi;

   Abstract : The interactions between polymers and components of biological systems are an important area of interest within the fields of tissue engineering, polymer chemistry, medicine and biomaterials. In order to create such a biomimetic material, it must show the inherent ability to reproduce or elicit a biological function. READ MORE

5. 3. Rational and combinatorial protein engineering for vaccine delivery and drug targeting

   Author : Maria Wikman; Stefan Ståhl; Carl A. K. Borrebaeck; KTH; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomedicine; affibody; affinity chromatography; biotin; combinatorial; delivery; phage display; Biomedicin; Microbiology; Mikrobiologi;

   Abstract : This thesis describes recombinant proteins that have been generated by rational and combinatorial protein engineering strategies for use in subunit vaccine delivery and tumor targeting.In a first series of studies, recombinant methods for incorporating immunogens into an adjuvant formulation, e.g. READ MORE

6. 4. Properties of Protein and Polymer Systems

   Author : Fredrik Carlsson; Avdelningen för Konstruktionsteknik; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Fysikalisk kemi; Physical chemistry; lysozyme; mica; surface; dimerization; precipitation; aggregate; cluster; complex; polyelectrolyte; protein; polymer;

   Abstract : Interactions of proteins with other proteins, with polymers and with surfaces are of great practical importance within for instance protein purification, drug delivery, and food technology. The aim of this work is to increase the understanding of protein-protein, protein-polyelectrolyte, and protein-surface interactions, particularly concerning the role of electrostatic interactions in these systems. READ MORE

7. 5. Platforms and strategies harnessing signaling pathways of multifactorial diseases by multispecific antibodies

   Author : Aman Mebrahtu; Johan Rockberg; Fredrik Y. Frejd; Janine Schuurman; KTH; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Antibodies; Bispecific antibodies; Multispecific affinity proteins; Protein engineering; Protein expression; Cancer; Immunotherapy; Autoimmunity; Systemic Lupus Erythematosus; Affibody molecules; AffiMab; Antikroppar; Bispecifika antikroppar; Multispecifika affinitets protein; Protein engineering; Protein uttryck; Cancer; Immunoterapai; Autoimmunitet; Systemic Lupus Erythematosus; Affibody molekyler; AffiMab; Biotechnology; Bioteknologi;

   Abstract : Abstract [ENG]Proteins govern a multitude of biological functions vital to sustain life. The ability to withstand diseases development and harboring a defense against foreign pathogens is attributed to the wonders of the immune system and the proteins and cells its comprised of. READ MORE