Search for dissertations about: "protein electrostatics"
Showing result 1 - 5 of 6 swedish dissertations containing the words protein electrostatics.
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1. Navigating the Cellular Crowd : Physicochemical Properties of Protein Surfaces as Evolved Interaction Guides
Abstract : The cellular interior is characterised by high concentrations of macromolecules. Compared with dilute conditions, the crowd modifies proteins' ability to fold, diffuse and, ultimately, carry out their biological functions. Cellular fitness depends on ensuring an adequate balance between interactivity and diffusivity. READ MORE
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2. Protein Interactions: Electrostatics and Ligand Binding
Abstract : This thesis deals with Ca2+ binding to proteins, electrostatic interactions in and between proteins as well as inter- and intramolecular interactions. A computer program was developed to determine Ca2+ binding constants from experimental titration data of proteins. READ MORE
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3. Diffusive interactions play an important role in protein stability and mobility : Investigations of the intracellular milieu using in-cell NMR
Abstract : Proteins are crucial for all cellular life. Every signal received by a cell, and every response to it, is mediated by proteins. Inside cells, these proteins diffusively sample each other’s surfaces, as they travel through the cytoplasm in search of their specific interaction partners. READ MORE
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4. Electrostatic Interactions In and Between Biomolecules
Abstract : Electrostatic interactions in bio-molecular systems are important not only in the living cell but also in more technical applications. Using molecular simulation as well as approximate theories the properties of a number of aqueous protein solutions have been studied. READ MORE
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5. Anisotropic Protein Interactions in Salt Solutions and at Interfaces: Coarse Grained Modeling
Abstract : Anisotropic protein interactions have a strong orientation dependence resulting from an uneven distribution of charged and hydrophobic residues on the protein surface. They play an important role in protein behaviors such as protein association, surface adsorption and phase separation. READ MORE