Search for dissertations about: "protein family protein stability"
Showing result 1 - 5 of 85 swedish dissertations containing the words protein family protein stability.
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1. The birth and growth of the protein folding nucleus : Studies of protein folding focused on critical contacts, topology and ionic interactions
Abstract : Proteins are among the most complex molecules in the cell and they play a major role in life itself. The complexity is not restricted to just structure and function, but also embraces the protein folding reaction. READ MORE
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2. From protein sequence to structural instability and disease
Abstract : A great challenge in bioinformatics is to accurately predict protein structure and function from its amino acid sequence, including annotation of protein domains, identification of protein disordered regions and detecting protein stability changes resulting from amino acid mutations. The combination of bioinformatics, genomics and proteomics becomes essential for the investigation of biological, cellular and molecular aspects of disease, and therefore can greatly contribute to the understanding of protein structures and facilitating drug discovery. READ MORE
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3. Structural Studies of Binding Proteins: Investigations of Flexibility, Specificity and Stability
Abstract : Binding proteins are present both in gram-negative and gram-positive bacteria. They are the recognition components of the ABC transport systems that transport different nutrients into the cell, and are in some cases also involved in chemotaxis. READ MORE
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4. The effect of sequence truncation and amino-acid substitutions on the biophysical properties of protein S and calbindin D9k
Abstract : Protein S is a modular protein and a cofactor in the protein C anticoagulant system. It consists of a Gla-module, a thrombin-sensitive loop, four EGF-modules and a SHBG-like module. READ MORE
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5. Prediction, Design and Determination of Protein Structures
Abstract : The three-dimensional structure of protein is encoded in its amino acid sequence. Modern structure prediction algorithms make it possible to predict the structure of small proteins using sequence information alone. READ MORE