Search for dissertations about: "protein glycation"

Showing result 1 - 5 of 15 swedish dissertations containing the words protein glycation.

  2. 1. Protein Damage Control during Embryonic Stem Cell Differentiation: Role of the Proteasome

    Author : Malin Hernebring; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Embryonic Stem Cells; Proteasome; Protein Carbonylation; Advanced Glycation End products; Cell Differentiation; Oxidative stress; Aging; RNAi;

    Abstract : During the lifespan of organisms ranging from yeast to humans, there is an accumulation of macromolecular damage. However, these organisms produce youthful progeny with low damage levels. This thesis focuses on how this is accomplished. READ MORE

  4. 2. Apolipoprotein A-I in glucose metabolism and amyloidosis

    Author : Oktawia Nilsson; Medicinsk proteinvetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Amyloidosis; Apolipoprotein A-I; beta cell; cardiovascular disease; cholesterol efflux; diabetes; glucose metabolism; glycation; high-density lipoprotein; insulin secretion;

    Abstract : The role of Apolipoprotein A-I (ApoA-I), the main protein component of HDL, in cholesterol transport and metabolism is well known and has been studied for more than four decades. More recently, ApoA-I protein has been shown to also have a positive role in glucose control by both stimulation of glucose uptake by muscles and by increasing glucose-stimulated pancreatic insulin secretion. READ MORE

  5. 3. On the importance of inflammation for personality traits and psychiatric morbidity

    Author : Petra Suchankova; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; inflammation; C-reactive protein; complement factor H; S100B; receptor for advanced glycation end products; polymorphism; gene expression; personality traits; suicidal behaviour; schizophrenia; depression; Flinders sensitive line;

    Abstract : Background: Pro-inflammatory mediators have been implicated in processes that could be both beneficial and toxic to cells in the brain. On the one hand balanced levels of these mediators favour e.g. READ MORE

  6. 4. The inflammatory and immunogenic properties of the receptor for advanced glycation end products and its ligand, high mobility group box chromosomal protein 1

    Author : Rille Pullerits; Göteborgs universitet; []
    Keywords : HMGB1; sRAGE; rheumatoid arthritis; inflammation; cytokines;

    Abstract : Rheumatoid arthritis (RA) is a chronic systemic inflammatory joint disease, the pathogenesis of which is complex, involving a wide range of molecules. High mobility group box chromosomal protein 1 (HMGB1) is a nuclear protein recently recognised as a pro-inflammatory cytokine which levels are increased in RA patients. READ MORE

  7. 5. Studies of high mobility group chromosomal protein 1 as a pro-inflammatory cytokine

    Author : Gail E Mullins; Karolinska Institutet; Karolinska Institutet; []
    Keywords : HMGB1; endothelial cells; pro-inflammatory; cytokine; RAGE;

    Abstract : High mobility group box chromosomal protein 1 (HMGB 1) is a nuclear protein recently recognised as a pro-inflammatory cytokine with implications both in acute and in chronic inflammation. HMGB1 has been reported to act as a late mediator of septic shock in mice. READ MORE