Search for dissertations about: "protein quality"

Showing result 1 - 5 of 449 swedish dissertations containing the words protein quality.

  1. 1. Protein Model Quality Assessment : A Machine Learning Approach

    Author : Karolis Uziela; Arne Elofsson; Liam McGuffin; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Protein Model Quality Assessment; structural bioinformatics; machine learning; deep learning; support vector machine; proq; Artificial Neural Network; protein structure prediction; Biochemistry towards Bioinformatics; biokemi med inriktning mot bioinformatik;

    Abstract : Many protein structure prediction programs exist and they can efficiently generate a number of protein models of a varying quality. One of the problems is that it is difficult to know which model is the best one for a given target sequence. Selecting the best model is one of the major tasks of Model Quality Assessment Programs (MQAPs). READ MORE

  2. 2. Protein Structure Prediction : Model Building and Quality Assessment

    Author : Björn Wallner; Arne Elofsson; Michael Levitt; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; protein structure prediction; proteinstrukturförutsägelse; Bioinformatics; Bioinformatik;

    Abstract : Proteins play a crucial roll in all biological processes. The wide range of protein functions is made possible through the many different conformations that the protein chain can adopt. The structure of a protein is extremely important for its function, but to determine the structure of protein experimentally is both difficult and time consuming. READ MORE

  3. 3. Exploring small heat shock protein chaperones by crosslinking mass spectrometry

    Author : Wietske Lambert; Biokemi och Strukturbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; cross-linking; mass spectrometry; protein-protein interactions; Hsp21; BS3; DTSSP; MALDI-TOF TOF; client protein; substrate; aggregation; unfolded protein; chaperone; Small heat shock protein; crosslinking;

    Abstract : Together with other molecular chaperones, small heat shock proteins are key components of the protein quality control system, which is comprised of several hundred proteins and acts to maintain proteome homeostasis in the cell. Small heat shock proteins bind unfolding proteins at an early stage, to prevent these from further unfolding and aggregating. READ MORE

  4. 4. Unlocking protein sequences : Advances in protein structure and ligand-binding site prediction

    Author : Aditi Shenoy; Arne Elofsson; Geoffrey J Barton; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; biokemi med inriktning mot bioinformatik; Biochemistry towards Bioinformatics;

    Abstract : The protein sequence determines how it will fold into its unique three-dimensional structure. Once folded, proteins perform their functions by interacting with other proteins or molecules called ligands within the cell. Experimental determination of protein structure and function is tedious. READ MORE

  5. 5. Seaweed as a sustainable source of food protein: maximizing seaweed protein content, protein recovery, and nutritional quality

    Author : João Pedro Trigo; Chalmers tekniska högskola; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; protein isolation; intestinal permeability; detergent; thermal water treatment; protein shift; wastewater; elemental compositional; macroalgae; gastrointestinal digestion; cultivation;

    Abstract : This thesis focuses on utilizing seaweed, such as Saccharina latissima and Ulva fenestrata , as sustainable food protein sources to complement terrestrial protein currently limited by land and water supply. While seaweed holds promise, its protein content is lower than pulses and antinutrients reduce protein nutritional quality. READ MORE