Search for dissertations about: "prothrombotic"
Showing result 1 - 5 of 34 swedish dissertations containing the word prothrombotic.
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1. The hemostatic pathway in ischemic stroke. Clinical studies of genetic variation and plasma protein measurements
Abstract : Although stroke is a common cause of death and disability in adults, there are few studies on stroke compared to other common diseases. A stroke could be either ischemic or hemorrhagic, but even within these two groups, disease etiology shows heterogeneity. READ MORE
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2. Platelet and leukocyte activation and their interaction : in experimental prothrombotic and inflammatory states
Abstract : Atherosclerotic disease is associated with inflammation and thrombosis, both of which involve multi-cellular activation and interaction. The present work has investigated the mechanisms of platelet leukocyte cross-talk in vitro, and explored the possibility of multi-cellular activation in vivo in prothrombotic and inflammatory models in healthy volunteers. READ MORE
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3. New diagnostic approaches for venous thromboembolism and thrombophilia
Abstract : Background: Venous thromboembolism is a serious disease comprising both pulmonary embolism and deep vein thrombosis. Venous thromboembolism causes considerable mortality and morbidity, with residual symptoms such as pulmonary hypertension and post thrombotic syndrome. READ MORE
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4. Platelet microparticles and hemostatic disturbances in renal insufficiency and cardiovascular disease
Abstract : Background: Chronic kidney disease (CKD) affect up to 10-15% of the population worldwide and is a growing global health problem. Diabetes, hypertension and renal diseases, such as glomerulonephritis, are the major cause of CKD in high- and middle-income countries. READ MORE
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5. Novel in vivo therapeutic approaches to Escherichia coli O157:H7 infection
Abstract : Shiga toxin (Stx), the unique virulence factor released by enterohemorrhagic Escherichia coli (EHEC), associated with gastrointestinal infection and in severe cases hemolytic uremic syndrome (HUS). Up until now, no effective therapies have been developed to control disease progression. READ MORE
