Search for dissertations about: "pyruvate dehydrogenase kinase"
Showing result 1 - 5 of 7 swedish dissertations containing the words pyruvate dehydrogenase kinase.
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1. Coupling mechanisms of insulin secretion - roles of mitochondrial metabolism and cAMP
Abstract : Type 2 diabetes is a disease that increases tremendously in the western world. It is characterized by insulin resistance and defects in insulin secretion. Insulin resistance is tightly linked to obesity, and usually precedes the onset of type 2 diabetes. READ MORE
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2. Bioelectrochemical Applications of Reactions Catalyzed by Immobilized Enzymes
Abstract : The sensitivity of biosensors can be increased substantially by incorporation in a substrate recycling scheme. Based on the amplification of NAD+/NADH by the recycling reaction catalyzed by glycerol dehydrogenase (GDH) and diaphorase, NAD+/NADH can be determined amperometrically with around 1000 times higher sensitivity than for the substrate sensing mode. READ MORE
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3. Protein phosphorylation in plant mitochondria
Abstract : Protein phosphorylation in the subcompartments of plant mitochondria was investigated by labelling with [gamma-32P]ATP and by SDS-PAGE/autoradiography. About 20 proteins in inside-out inner mitochondrial membranes from potato tubers were phosphorylated by endogenous protein kinases when incubated with [gamma-32P]ATP. READ MORE
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4. Molecular regulators of glucose and lipid metabolism in skeletal muscle
Abstract : Skeletal muscle is a primary site of insulin action and insulin-stimulated glucose transport and occupies a center stage in maintaining whole body glucose and lipid homeostasis. Another key feature of a healthy skeletal muscle is its ability to switch between utilization of lipids and glucose as fuel in response to feeding or fasting respectively. READ MORE
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5. Skeletal muscle HIF-1 and exercise
Abstract : Regular physical activity prevents and improves a number of disease conditions and reduces the risk for premature death substantially. From a clinical as well as a basic science point of view it is important to create a more fundamental understanding of the molecular mechanisms that contribute to the improved functional capacity induced by regular physical activity. READ MORE