Search for dissertations about: "quetiapine"

Showing result 1 - 5 of 10 swedish dissertations containing the word quetiapine.

2. 1. PET applications in schizophrenia : Functional and pharmacological dopamine studies

   Author : Ola Gefvert; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Schizophrenia; PET; dopamine synthesis rate; dopamine D2 receptor occupancy; atypical antipsychotics; quetiapine; risperidone microsphere depot; Neurovetenskap; Neurology; Neurologi; Psychiatry; psykiatri;

   Abstract : Schizophrenia is a group of disorders with a worldwide lifetime prevalence of 0.85%. Thefunctional outcome of the disorder seem stable from the first systematic outcome studies to thepresent day, and vary only with changes in diagnostic criteria. READ MORE

4. 2. Bipolar disorders: Subtypes, treatments, and health inequalities

   Author : Alina (Aikaterini) Karanti; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bipolar disorders; drug therapy; lithium; lamotrigine; quetiapine; mood stabilizers; antidepressants; electroconvulsive therapy; psychotherapy; psychoeducation; comorbidity; socioeconomic factors; healthcare disparity; gender; education;

   Abstract : This thesis comprises five studies based on prospective, longitudinal data from the Swedish national quality register BipoläR. Study I examined the differences between bipolar subtype I and II with respect to clinical features, course of illness, comorbidity, and socioeconomic factors. READ MORE

5. 3. Treatments and outcomes in bipolar disorder

   Author : Erik Joas; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bipolar disorder; lithium; psychoeducation; CYP2C19; antidepressants; epidemiology; valproate; quetiapine; olanzapine; suicide;

   Abstract : Bipolar disorder is defined by recurring mood episodes and patients have a markedly increased risk of suicide. Pharmacological and psychological treatments for bipolar disorder have proven efficacy in clinical trials yet the generalizability of current evidence to routine clinical practice is contested. READ MORE

6. 4. Drug-drug interactions : from knowledge base to clinical impact

   Author : Marine Andersson; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Drug usage has increased steadily, and the more drugs used, the higher the risk for adverse effects or loss of effect due to drug-drug interactions. For drug prescribers it is difficult to know what drugs a patient is taking and whether they interact. READ MORE

7. 5. Utility of combined treatment with antipsychotic and antidepressant drugs : scientific rationales and clinical implications

   Author : Carl Björkholm; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The atypical antipsychotic drug (APD) clozapine is the most efficacious APD in treatment-resistant schizophrenia including negative symptoms and cognitive impairment, and still lacks extrapyramidal side effects (EPS). Clozapine, which also possesses an antidepressant effect and can be used as monotherapy in bipolar disorder, has a broad receptor binding profile with higher affinity for the α2-adrenoceptor and several serotonergic receptors than D2 receptor, enhances dopamine output in the medial prefrontal cortex (mPFC) and facilitates glutamatergic NMDA receptor-mediated transmission in pyramidal cells in the same brain region. READ MORE