Search for dissertations about: "radical scavenger"

Showing result 1 - 5 of 25 swedish dissertations containing the words radical scavenger.

  1. 1. Experimental cardiopulmonary cerebral resuscitation : with special reference to cerebral eicosanoid production and free radical scavengers

    Author : Xiaoli Liu; Marianne Forsman; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anaesthesiology and intensive care; cerebral resuscitation; reperfusion damage; oxidative injury; eicosanoid; free radical scavenger; neurological function; alkaline buffer; S-PBN; PBN; Anestesiologi och intensivvård; Anaesthetics and intensive care; Anestesiologi och intensivvård; Anestesiologi; Anaesthesiology;

    Abstract : Reperfusion injury after restoration of spontaneous circulation (ROSC) is often considered one of the predominant factors in determining neurological outcome in cardiac arrest. Therefore one of the main targets of experimental and clinical studies has been to mitigate this reperfusion injury. READ MORE

  2. 2. Alpha-1-microglobulin: Innate defence against pathological oxidation

    Author : Magnus Gram; Infektionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; alpha-1-microglobulin; pathological oxidation; hemoglobin; heme; radiation; oxidation; ROS; hemoglobin and heme antagonist; radical scavenger;

    Abstract : Oxidative stress has been implicated as an important factor in the progression of many diseases. An imbalance in the redox-system may cause oxidation of cells and molecules, which might subsequently lead to tissue damage. READ MORE

  3. 3. Astrocytic communication and cell death during metabolic depression and oxidative stress

    Author : Christina Nodin; Göteborgs universitet; []
    Keywords : astrocyte; gap junction; ATP; ROS; oxidative stress; Annexin V; AIF; programmed cell death; Nrf2; scavenger; iodoacetate; SIN-1;

    Abstract : Stroke is a major cause of death and adult disability in the western world. Most often, stroke is caused by the occlusion of a brain artery. Within the perfusion territory of the occluded vessel, various degrees of necrotic and delayed programmed cell death will occur if the occlusion persists, leading to expanding tissue damage. READ MORE

  4. 4. Impact of sepsis and HIV-1 infection on neutrophil radical production, lipids and lipoproteins

    Author : Börje Åkerlund; Karolinska Institutet; Karolinska Institutet; []
    Keywords : sepsis; HIV-1 infection; lipoprotein changes; free oxygen radicals; neutrophils; lipidperoxidation; oxidative stress; N-acetylcysteine;

    Abstract : In clinical sepsis a decrease in total serum cholesterol caused by reduced HDL and LDL cholesterol occurred early in the course of the infection with a normalisation after 2 months. This "sepsis HDL" was shown to contain the acute phase reactant SAA and it affected several functions of the neutrophil. READ MORE

  5. 5. Diabetes-induced Alterations in Renal Microcirculation and Metabolism

    Author : Fredrik Palm; Per Liss; Peter Hansell; Per-Ola Carlsson; Gerald DiBona; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology; diabetes mellitus; kidney; nephropathy; oxygen tension; haemodynamic; nitric oxide; oxygen consumption; radical oxygen species; polyol pathway; Fysiologi; Physiology; Fysiologi;

    Abstract : Diabetes-induced renal complications, i.e. diabetes nephropathy, are a major cause of morbidity and mortality. The exact mechanism mediating the negative influence of hyperglycaemia on renal function is unclear, although several hypotheses have been postulated. READ MORE