Search for dissertations about: "radionuclide investigation"

Showing result 1 - 5 of 12 swedish dissertations containing the words radionuclide investigation.

2. 1. In situ measurements of radionuclide concentration in soil : An investigation into detector properties and methods

   Author : Johan Kastlander; Christoph Bargholtz; Mats Isaksson; Stockholms universitet; []
   Keywords : In situ gamma-ray spectrometry; LaBr3; CdTe; Cs-137; soil samples; fysik; Physics;

   Abstract : In case of a release of radioactive nuclides into the environment it is necessary to  have reliable methods to estimate the potential effect on people and the ecosystem. In this context the total activity deposited, the elemental composition and the depth distribution are of importance. READ MORE

4. 2. Radionuclide Production with PET Cyclotrons, Applications and Preclinical Experiments

   Author : Jonathan Siikanen; Lund Medicinsk strålningsfysik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Radionuclide production; Solid target; Water target; Cyclotron; PET; SPECT; 18F; 89Zr;

   Abstract : Nuclear medicine is based on the radiotracer principle of George de Hevesy and the magic bullet concept by Ehrlich and focuses on the diagnosis, the treatment of diseases and the investigation of normal states within the human body using radiopharmaceuticals. A radiopharmaceutical is an atom or a chemical compound in which one or several atoms are replaced with a radionuclide. READ MORE

5. 3. Radioimmunotherapy in Experimental Head and Neck Squamous Cell Carcinoma : Tumour-targeting in vitro and in vivo

   Author : Junping Cheng; Matti Anniko; Mats Engström; Vladimir Tolmachev; Torgny Stigbrand; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Otorhinolaryngology; squamous cell carcinoma; radioimmunotherapy; cell line; tumour targeting; radionuclide; nude mice; Otorhinolaryngologi; Otorhinolaryngology; Otorhinolaryngologi;

   Abstract : Radioimmunotherapy (RIT) has been shown to be a practicable way to treat head and neck squamous cell carcinoma. A specific antibody recognizes the charasteristic structure of tumour cells when loaded with cytotoxic agents (toxins, drugs, radionuclides, etc). READ MORE

6. 4. Assessment of tubal infertility with radionuclide-labelled particles and falloscopy

   Author : Steffan Lundberg; Karolinska Institutet; Karolinska Institutet; []
   Keywords : fallopian tube; falloposcopy; hysterosalpingography; radionuclide hysteropingography; tubal infertility; tubal investigation; tubal transport;

   Abstract : The fallopian tubes are of central importance for human reproduction in vivo. Damage to the tubal internal mucosa can result in disturbance of sperm and ovum transport. About 40% of infertile women have tubal disease as their main cause of infertility. READ MORE

7. 5. Towards Personalized Cancer Therapy : New Diagnostic Biomarkers and Radiosensitization Strategies

   Author : Diana Spiegelberg; Marika Nestor; Bo Stenerlöw; Johan Lennartson; Theodosia Maina-Nock; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tumor targeting; radionuclide targeting; HSP90 inhibition; AT13387; radiosensitization; molecular imaging; combination treatment; EGFR; CD44v6; Biomedical Radiation Science; Biomedicinsk strålningsvetenskap;

   Abstract : This thesis focuses on the evaluation of biomarkers for radio-immunodiagnostics and radio-immunotherapy and on radiosensitization strategies after HSP90 inhibition, as a step towards more personalized cancer medicine. There is a need to develop new tracers that target cancer-specific biomarkers to improve diagnostic imaging, as well as to combine treatment strategies to potentiate synergistic effects. READ MORE