Search for dissertations about: "rational design"

Showing result 1 - 5 of 210 swedish dissertations containing the words rational design.

  2. 1. Embodying Openness: A Pragmatist Exploration into the Aesthetic Experience of Design Form-Giving

    Author : Ariana Amacker; Göteborgs universitet; []
    Keywords : HUMANIORA; HUMANITIES; Design research; pragmatism; aesthetic experience; form-giving; arts-based learning;

    Abstract : This thesis explores the tension between a reflective view of design and design as an embodied, aesthetic experience. Most research exploring the nature of design follows a tradition of practice-based design research, which aims to empirically establish what constitutes design by studying what designers do and say. READ MORE

  4. 2. Catalysis and Site-Specific Modification of Glutathione Transferases Enabled by Rational Design

    Author : Sofia Håkansson Hederos; Lars Baltzer; Kerstin Broo; Linköpings universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Catalysis; Glutathione Transferases; Rational design; Protein design; Site-specific modification; thiolester hydrolysis; Enzyme engineering; Enzymteknik;

    Abstract : This thesis describes the rational design of a novel enzyme, a thiolester hydrolase, derived from human glutathione transferase (GST) A1-1 by the introduction of a single histidine residue. The first section of the thesis describes the design and the determination of the reaction mechanism. READ MORE

  5. 3. Protein Engineering by Directed Evolution and Rational Design

    Author : Torbjörn Gräslund; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; ion-exchange chromatography; subtilisin; Klenow DNA polymerase; Taq DNA polymerase; directed evolution; rational design; charge engineering; phosphonylating inhibitor; phage display; circular dichroism; protein A; Bioengineering; Bioteknik;

    Abstract : .... READ MORE

  6. 4. On the Nature and Origin of Recognition in Molecularly Imprinted Polymers. : Paths Towards Their Rational Design

    Author : Håkan S. Andersson; Ann-Christin Koch-Schmidt; Klaus Mosbach; Maria Kempe; Högskolan i Kalmar; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular imprinting; molecular recognition; Biokemi; Biochemistry;

    Abstract : .... READ MORE

  7. 5. Holistic approach in engineering design - controlling risks from accidental hazards in bridge design

    Author : Ivar Björnsson; Avdelningen för Konstruktionsteknik; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; design; codes; accidental; extreme; bridges; holistic; approach; robustness; risk; reliability; uncertainty;

    Abstract : Engineering design, in concise terms, is what engineers do using what they know. It is the underlying decision making activity that determines what is to be built and how it should be built. An ever present requirement in engineering design is that the structure should be safe. READ MORE