Search for dissertations about: "rational drug use"

Showing result 1 - 5 of 41 swedish dissertations containing the words rational drug use.

2. 1. Psychoactive prescription drug use disorders, misuse and abuse : Pharmacoepidemiological aspects

   Author : Micaela Tjäderborn; Staffan Hägg; Johan Ahlner; Anna Jönsson; Morten Andersen; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Psychoactive prescription drugs; psychotropic drugs; prescription drug use disorders; prescription drug misuse; abuse; pharmacovigilance; drug utilization; pharmacoepidemiology;

   Abstract : Background: There is a widespread and increasing use of psychoactive prescription drugs, such as opioid analgesics, anxiolytics, hypnotics and anti-epileptics, but their use is associated with a risk of drug use disorder, misuse and abuse. Today, these are globally recognized and emerging public health concerns. READ MORE

4. 2. Statistics on local drug sales: A tool to identify problem areas and to follow effects of education on drug use

   Author : Anders Ekedahl; Kardiovaskulär forskning - epidemiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; unused drugs; Pharmacological sciences; toxikologi; farmaci; farmakognosi; Farmakologi; toxicology; pharmacognosy; pharmacy; producer independent information; drug sales statistics;

   Abstract : Aims: 1) To assess if drug sales data indicate differences in morbidity, mortality, socio-economic conditions and deviating prescribing habits among physicians; 2) to identify areas for educational interventions and to analyse changes in prescribing after educational activities. In addition, an effort was made to estimate differences between pharmacy sales and purchases by the population, and the amount and value of unused drugs returned to pharmacies. READ MORE

5. 3. In vitro characterization of nanodrugs at model lipid membranes

   Author : Rickard Frost; Chalmers tekniska högskola; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; in vitro screening; nanomedicine; drug delivery; drug carrier; supported lipid bilayer; QCM-D; nanoparticle; cell membrane;

   Abstract : The use of nano-sized drug carriers to improve the efficiency of drug delivery has become well established during the past decades. New nanoparticle (NP) formulations for the administration of biopharmaceuticals (e.g. proteins and peptides) emerge at an increasing rate and the need for methods to evaluate their properties is expanding. READ MORE

6. 4. Socioeconomic differences in drug use among older people : trends, polypharmacy, quality and new drugs

   Author : Syed Imran Haider; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Pharmacoepidemiology; drug utilization; polypharmacy; inappropriate drug use; drug-drug interactions; new drugs; comorbidity; registers; cross-sectional; population-based; elderly; equity; socioeconomic position; education; occupation; income;

   Abstract : Polypharmacy and potentially inappropriate drug use (IDU) is a major patient safety and public health concern in the elderly, resulting in an increased likelihood of adverse drug reactions, drug-drug interactions (DDI), hospitalization, poor quality of life and mortality. This doctoral thesis investigated the complex relationship between drug use and socioeconomic position (SEP) and characterized the drug use, quality of prescribing, development of drug use over time, and use of new drugs in the elderly. READ MORE

7. 5. Rational and combinatorial protein engineering for vaccine delivery and drug targeting

   Author : Maria Wikman; Stefan Ståhl; Carl A. K. Borrebaeck; KTH; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomedicine; affibody; affinity chromatography; biotin; combinatorial; delivery; phage display; Biomedicin; Microbiology; Mikrobiologi;

   Abstract : This thesis describes recombinant proteins that have been generated by rational and combinatorial protein engineering strategies for use in subunit vaccine delivery and tumor targeting.In a first series of studies, recombinant methods for incorporating immunogens into an adjuvant formulation, e.g. READ MORE