Search for dissertations about: "receptor density"

Showing result 1 - 5 of 256 swedish dissertations containing the words receptor density.

2. 1. Genetic Variability in Human Bone Phenotypes : The Vitamin D Receptor Gene and the Estrogen Receptor-α Cofactor RIZ Gene

   Author : Elin Grundberg; Andreas Kindmark; Östen Ljunggren; Helena Brändström; André G. Uitterlinden; Uppsala universitet; []
   Keywords : Medicine; Bone mineral density; candidate gene approach; polymorphism; the vitamin D receptor; the estrogen receptor α; RIZ1; cofactor; allelic imbalance; Medicin;

   Abstract : Important candidate genes to human bone phenotypes are those involved in the regulation of hormonal action, such as the vitamin D receptor (VDR) and the estrogen receptor-α (ERα) genes and their cofactors. RIZ1 is a specific ERα cofactor proved to strongly enhance the function of the ERα. READ MORE

4. 2. Structure and function of the HDL receptor SR-BI : scavenger receptor class B type I

   Author : Magnus S.C. Johnson; Göteborgs universitet; []
   Keywords : SR-BI; HDL; Cholesterol; Scavenger receptor; Apoptosis; Ovary; Gallbladder; Peroxisome;

   Abstract : Low plasma levels of high-density lipoprotein (HDL) and high levels of low-density lipoprotein (LDL) are well-recognized risk factors for cardiovascular disease. The uptake and degradation of LDL cholesterol have been characterized in detail at the molecular level. Less is known about the metabolism and cellular uptake of HDL cholesterol. READ MORE

5. 3. Vascular receptor changes in ischemic stroke

   Author : Emelie Stenman; Lund Medicin; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vascular receptor changes; Ischemic stroke; Endothelin; Angiotensin; Cardiovascular system; Kardiovaskulära systemet; Pharmacological sciences; pharmacognosy; pharmacy; farmakognosi; farmaci; toxikologi; toxicology; Farmakologi;

   Abstract : The present thesis aimed to examine how ischemic stroke affects the vascular endothelin and angiotensin systems in cerebral arteries. To study vascular receptor changes in ischemic stroke transient focal ischemia was induced in rats. READ MORE

6. 4. Studies on scavenger receptor class B type I and genes implicated in foam cell formation

   Author : Per-Arne Svensson; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; scavenger receptor class B type I; high-density lipoprotein; oxidized low-density lipoprotein; macrophages; expression profiling;

   Abstract : The risk of atherosclerosis correlates with plasma levels of low-density lipoprotein (LDL) cholesterol and is inversely correlated to plasma levels of high-density lipoprotein (HDL) cholesterol. Accumulation of oxidized LDL (oxLDL) by arterial macrophages is a key event in the development of atherosclerosis. READ MORE

7. 5. Megalin, an Endocytotic Receptor with Signalling Potential

   Author : Mårten Larsson; Lars Rask; Bo Åkerström; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Megalin; LRP-2; Postsynaptic density-95; Retinol-binding protein; Oligodendrocytes; Central nervous system; Biokemi; Biochemistry; Biokemi;

   Abstract : Megalin is an endocytotic receptor belonging to the low-density lipoprotein family. It has often been viewed only as merely a scavenger receptor of absorptive and secretory epithelia. Recent work has revealed that the megalin intracellular domain contains several motifs potentially binding proteins involved in signal transduction. READ MORE