Search for dissertations about: "receptor specificity"

Showing result 1 - 5 of 202 swedish dissertations containing the words receptor specificity.

  2. 1. Galanin receptor ligands

    Author : Johan Runesson; Ülo Langel; Lena Mäler; Stockholms universitet; []
    Keywords : Galanin; GALP; GPCR; Agonist; GalR; Chimeric peptide; Inositol phosphate production; Receptor specificity; Neurochemistry and Molecular Neurobiology; neurokemi med molekylär neurobiologi;

    Abstract : In the nervous system galanin primarily displays a modulatory role. The galaninergic system consists of a number of bioactive peptides with a highly plastic expression pattern and three different receptors. The lack of receptor subtype selective ligands and antibodies have severely hampered the charac-terization of this system. READ MORE

  4. 2. Human papillomavirus tropism : determinants of viral tissue specificity

    Author : Nitesh Mistry; Magnus Evander; Ola Forslund; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; papillomavirus; receptor; heparan sulfate; pI; lactoferrin; lactoferricin; transcription; long control region; tropism; Virology; Virologi;

    Abstract : Cervical cancer is the second most common cancer among women worldwide and human papillomavirus (HPV) is a prerequisit for the development of this cancer. HPV belongs to the Papillomaviridae family and infects the basal layer of epithelial cells where it generally progresses into warts or condylomas. READ MORE

  5. 3. Novel Methods for Analysis of Heterogeneous Protein-Cell Interactions : Resolving How the Epidermal Growth Factor Binds to Its Receptor

    Author : Hanna Björkelund; Karl Andersson; Lars Gedda; Yosef Yarden; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heterogeneity; Kinetics; EGFR; HER2; LigandTracer; Interaction Map; Internalization; Specificity; Medical Science; Medicinsk vetenskap;

    Abstract : Cells are complex biological units with advanced signalling systems, a dynamic capacity to adapt to its environment, and the ability to divide and grow. In fact, they are of such high level of complexity that it has deemed extremely difficult or even impossible to completely understand cells as complete units. READ MORE

  6. 4. The CD40 Receptor - Target,Tool and Technology

    Author : Peter Ellmark; Institutionen för immunteknologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; serology; transplantation; Immunologi; serologi; SPIRE; mammalian; library; cDNA; selection; receptor revision; phage display; scFv; human; CD40; antibodies;

    Abstract : CD40 is a cell surface receptor of pivotal importance that is expressed on several of the cells in the immune system. It is critical for many important events, such as T cell dependent B cell activation, isotype switching, somatic mutation and generation of B cell memory. READ MORE

  7. 5. Identification and Characterization of the Moraxella catarrhalis IgD-binding Protein MID

    Author : Andrea Möllenkvist; Malmö Klinisk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; receptor; structure; phase variation; MID; IgD; Moraxella catarrhalis; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Abstract : Moraxella catarrhalis is now an established human pathogen that frequently colonizes the upper respiratory tract causing most importantly otitis media in children. It has also been associated with sinusitis, laryngitis and lower respiratory tract infections in adults with predisposing conditions such as chronic obstructive pulmonary disease (COPD). READ MORE