Search for dissertations about: "release factor"

Showing result 1 - 5 of 506 swedish dissertations containing the words release factor.

  2. 1. Platelet activation and tissue factor release in hemolytic uremic syndrome

    Author : Anne-lie Ståhl; Lund Pediatrik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hemolytic uremic syndrome; platelets; tissue factor; LPS; Shiga toxin; complement system; factor H; clusterin;

    Abstract : Hemolytic uremic syndrome (HUS) is a clinical syndrome characterized by microangiopathic hemolytic anemia, thrombocytopenia and acute renal failure. There are two subtypes: typical HUS associated with enterohemorrhagic E. coli (EHEC) and atypical HUS associated with uninhibited activation of the alternative pathway of complement. READ MORE

  4. 2. Hepatocyte growth factor : Studies on local and systemic release and effects during infectious disease; in vivo and in vitro

    Author : Fariba Nayeri; Minoca Niste'r; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : The interaction of mesenchymal and epithelial cells that occurs after organ injuries results in enhanced production of cytokines, such as hepatocyte growth factor (HGF). HGF is a glycoprotein with unique properties that contribute to wound healing after injuries. READ MORE

  5. 3. Versatile Implementations of an Improved Cell-Free System for Protein Biosynthesis : Functional and structural studies of ribosomal protein L11 and class II release factor RF3. Novel biotechnological approach for continuous protein biosynthesis

    Author : Lamine Bouakaz; Måns Ehrenberg; Richard Buckingham; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Protein synthesis; translation termination; ribosome; release factor; cell-free system; missense error; gel filtration; affinity chromatography; Molekylärbiologi; Molecular biology; Molekylärbiologi;

    Abstract : Advances in genetics, proteomics and chromatography techniques have enabled the successfully generation of a cell-free bacterial translation system composed of highly pure and active components. This system provided an ideal platform for better elucidating the mechanism of each individual step of the prokaryotic protein biosynthesis and the function of the translation factors involved in the process. READ MORE

  6. 4. Structural and functional studies of factor V in health and disease

    Author : Mårten Steen; Malmö Klinisk kemi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk kemi; Clinical chemistry; APC resistance and hemophilia; thrombosis; factor VIII; coagulation; factor V;

    Abstract : The homologous blood coagulation factors V (FV) and factor VIII (FVIII) are important at sites of vascular injury for the amplification of the clotting cascade. Activated FV (FVa) serves as a cofactor to the enzyme activated factor X (FXa) in the activation of prothrombin. This complex is called the prothrombinase complex. READ MORE

  7. 5. lac of Time : Transcription Factor Kinetics in Living Cells

    Author : Petter Hammar; Johan Elf; Antoine van Oijen; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; gene regulation; transcription factor; lac operon; facilitated diffusion; single molecule imaging; Molecular Biotechnology; Molekylär bioteknik;

    Abstract : Gene regulation mediated by transcription factors (TFs) is essential for all organisms. The functionality of TFs can largely be described by the fraction of time they occupy their regulatory binding sites on the chromosome. DNA-binding proteins have been shown to find their targets through facilitated diffusion in vitro. READ MORE