Search for dissertations about: "release rate"

Showing result 1 - 5 of 493 swedish dissertations containing the words release rate.

  1. 1. Spinal Acetylcholine Release : Mechanisms and Receptor Involvement

    Author : Mahinda Kommalage; Urban Höglund; Ernst Brodin; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; acetylcholine release; spinal antinociception; nicotinic receptor; serotonin; GABA; Neurovetenskap; Neurology; Neurologi;

    Abstract : Impulses coming from peripheries are modified in the spinal cord and transmitted to the brain. Several neurotransmitters have been involved in the processing of impulses in the spinal dorsal horn. Acetylcholine (ACh) is one of many neurotransmitters involved in the regulation of nociception in the spinal cord. READ MORE

  2. 2. Poly(Lactide-co-Glycolide) in Controlled-Release Pharmaceuticals - Release Mechanisms

    Author : Susanne Fredenberg; Avdelningen för kemiteknik; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; PLGA; Poly lactide-co-glycolide ; Release mechanism; Diffusion; Controlled Release; Degradation; Protein;

    Abstract : Controlled-release formulations reduce the frequency of injections and better maintain plasma concentrations within the therapeutic window. Poly(D,L-lactide-co-glycolide) (PLG) is currently the most frequently used biodegradable polymer for this application. READ MORE

  3. 3. Mesoporous magnesium carbonate as a drug delivery vehicle for stabilising amorphous drugs and regulating their release rate

    Author : Peng Zhang; Maria Strømme; Niklas Hedin; Uppsala universitet; []
    Keywords : mesoporous; magnesium carbonate; drug delivery; solubility enhancement; bioavailability; pharmacokinetics; diffusion release; controlled release; Teknisk fysik med inriktning mot nanoteknologi och funktionella material; Engineering Science with specialization in Nanotechnology and Functional Materials;

    Abstract : In today’s drug discovery, the number of candidate drugs based on new molecular entities with poor aqueous solubility is increasing. Since poor aqueous solubility of an active pharmaceutical ingredients (APIs) is associated with low bioavailability and thus limite their therapeutic effect, this is often a great challenge in the development of new drugs when oral administration is the preferred route of administration. READ MORE

  4. 4. Semipermeable membrane devices as integrative tools for monitoring nonpolar aromatic compounds in air

    Author : Hanna Söderström; Mats Tysklind; Per-Anders Bergqvist; Jochen F. Muller; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Environmental chemistry; air pollution; alkyl-PAHs; atmosphere; bioavailability; boundary layer; diffusive sampling; emissions; integrative; membrane; monitoring; nitro-PAHs; PAHs; particles; passive samplers; PCBs; plants; PRCs; release rate; sampler design; sources; SPMDs; traffic; uptake rate; wind effect; wood burning; Miljökemi; Environmental chemistry; Miljökemi;

    Abstract : Air pollutants pose a high risk for humans, and the environment, and this pollution is one of the major environmental problems facing modern society. Active air sampling is the technique that has been traditionally used to monitor nonpolar aromatic air pollutants. READ MORE

  5. 5. Sustained and triggered release by microencapsulation

    Author : Viktor Eriksson; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; cellulose; controlled release; microencapsulation; solution blown;

    Abstract : Uncontrolled growth of microorganisms is problematic in areas ranging from wound care to aquaculture and ship hulls. In chronic and hard-to-heal wounds, a bacterial biofilm can impair wound healing. READ MORE