Search for dissertations about: "repeats"

Showing result 1 - 5 of 209 swedish dissertations containing the word repeats.

  2. 1. Variation in length of proteins by repeats and disorder regions

    Author : Rauan Sagit; Arne Elofsson; Andrey Kajava; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; protein length; repeats; domain repeats; protein evolution; duplication; tandem duplication; intrinsic disorder; intrinsically disordered; variation in length; insertion; deletion; recombination; expansion; contraction; Biochemistry; biokemi;

    Abstract : Protein-coding genes evolve together with their genome and acquire changes, some of which affect the length of their protein products. This explains why equivalent proteins from different species can exhibit length differences. READ MORE

  4. 2. Intrinsic disorder and tandem repeats - match made in evolution : Computational studies of molecular evolution

    Author : Oxana Lundström; Arne Elofsson; Liberles-Siltberg Jessica; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Protein evolution; intrinsically disordered proteins IDPs ; tandem repeats; short tandem repeats STRs ; genetic variation; orphan proteins; GC content; human STR variation; colorectal cancer; gene expression; biokemi med inriktning mot bioinformatik; Biochemistry towards Bioinformatics;

    Abstract : Proteins are both the building blocks and workers of the cell, carrying out most of the important functions. For a long time, their structure has been regarded as the primary factor for their function, but intrinsically disordered proteins demonstrate an alternative to this paradigm. READ MORE

  5. 3. Trinucleotide repeats and neuropsychiatric phenotypes

    Author : Qiu-Ping Yuan; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Trinucleotide; repeat expansion; psychiatric disorder; gene; spastic paraplegia;

    Abstract : Genetic studies of affective disorders have yielded several chromosomal regions suggestive for linkage. Linkage analysis was performed in five families with unipolar affective disorder, collected from northern Sweden. Four candidate regions on chromosomes 16, 18, 21 and 4p were excluded. READ MORE

  6. 4. Software Tools and Algorithms for Shotgun Sequence Assembly

    Author : Martti T. Tammi; Bruce Roe; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Shotgun sequencing; multiple alignment; fragment assembly; repeats; sequencing error; Genetik; Clinical genetics; Klinisk genetik; Medical Genetics; medicinsk genetik;

    Abstract : During the last ten years, a genomics revolution has changed the ways biological research is carried out. The draft sequence of the human genome is available, as well as the sequence of 84 other completed genomes. READ MORE

  7. 5. A Genetic Survey of the Pathogenic Parasite Trypanosoma cruzi

    Author : Anh-Nhi Tran; Lena Åslund; John Kelly; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular genetics; Trypanosoma cruzi; Chagas ; gene discovery; EST; sequencing; DGC3; repeats; gene family; CL Brener; trypanothione synthetase; TcTRS locus; alleles; polymorphism; RNA-binding protein; TcPTB; stage-specific expression; Genetik; Genetics; Genetik; medicinsk genetik; Medical Genetics;

    Abstract : Trypanosoma cruzi, the causative agent of Chagas´ disease, is an evolutionarily ancient species with distinct biological and immunological characteristics. A fundamental understanding of the basic biology of the parasite is necessary in order to develop reliable therapeutic and prophylactic agents against T. cruzi. We have, as a part of the T. READ MORE