Search for dissertations about: "reproductive models"

Showing result 1 - 5 of 86 swedish dissertations containing the words reproductive models.

  2. 1. Reproductive toxicology of endocrine disruptors : effects of cadmium, phthalates and phytoestrogens on testicular steroidogenesis

    Author : David Gunnarsson; Gunnar Selstam; Gunnar Nordberg; Per Leffler; Henrik Leffers; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Endocrine disruptors; reproductive toxicology; cadmium; phthalates; DEHP; MEHP; phytoestrogens; steroidogenesis; testosterone; Leydig cell; Molecular biology; Molekylärbiologi;

    Abstract : A number of investigations during the last two decades describe adverse trends in male reproductive health, which have been proposed to be caused by environmental factors with endocrine disrupting properties. In contrast to many other toxicants, endocrine disruptors often do not show linear dose-response relationships typical of those found in traditional toxicological studies. READ MORE

  4. 2. Host epithelium integrity in the female reproductive tract during Neisseria gonorrhoeae infection

    Author : Linda Weyler; Helena Aro; Lene Rasmussen; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Female reproductive tract; Neisseria gonorrhoeae; VK2 E6E7 cells; DNA damage; cell cycle; mitosis; restriction endonucleases; infection models; molekylär biovetenskap; Molecular Bioscience;

    Abstract : Neisseria gonorrhoeae infections are asymptomatic in approximately fifty percent of the affected women. Left untreated, this can develop into a long-term inflammatory state with detrimental secondary complications such as ectopic pregnancy and sterility. Furthermore, studies have shown that N. READ MORE

  5. 3. Behavioral effects of female sex steroid hormones : models of PMS and PMDD in Wistar rats

    Author : Magnus Löfgren; Torbjörn Bäckström; Inga-Maj Johansson; Per Södersten; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; PMS; PMDD; rats; progesterone; estradiol; behavior; individual response; stress interaction; tolerance; withdrawal; learning and memory; anxiety.; Biological research on drug dependence; Biologisk beroendeforskning; Endocrinology; Endokrinologi; Obstetrics and gynaecology; Obstetrik och gynekologi; Pharmacological research; Farmakologisk forskning; Obstetrics and gynaecology; Obstetrik och gynekologi; Psychology; Psykologi; obstetrik och gynekologi; Obstetrics and Gynaecology;

    Abstract : Background Animal models can be used to mimic human conditions of psychopathology, and also as pre-clinical models to evaluate candidate drugs. With hormonal treatment it is possible to produce behavior in the rat which corresponds to the mental symptoms of pre-menstrual syndrome (PMS), and pre-menstrual dysphoric disorder (PMDD). READ MORE

  6. 4. To desire and to choose : aspects of women's and men's urge to have children

    Author : Marianne Wikman; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Urge for children; ambivalence; reproductive choice; attitudes towards reproduction; conflicting views; childbearing motivation; gastrin; biopsychosodal;

    Abstract : The aim of this study was to increase available knowledge about women's and men’s desire for pregnancy and for a child/children to serve as a basis for further studies of problems and inconsistencies in the reproductive sphere. The motivation to become a parent was hypothesized as being not only of an existential, social, interpersonal and intrapsychic character but also a biologically anchored personality trait. READ MORE

  7. 5. In vitro and in vivo studies on the toxicology of di-n-butyl phthalate (DBP) : Effects on reproductive, endocrine, and immune systems

    Author : Liselott Källsten; Oskar Karlsson; Paula Pierozan; Jonathan W. Martin; Jorma Toppari; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Dibutyl phthalate; Endocrine disrupting chemicals; Male reproductive health; Phthalates; Immunotoxicity; Toxicology; Steroidogenesis; Environmental Sciences; miljövetenskap;

    Abstract : Chemical pollution is an increasing societal problem and has a major impact on human and environmental health. One important source of chemical pollution is plastic, which contains many different compounds with often largely unknown hazards. READ MORE