Search for dissertations about: "rheumatoid factor"

Showing result 1 - 5 of 164 swedish dissertations containing the words rheumatoid factor.

2. 1. Early rheumatoid arthritis : biomarkers and hormonal factors in relation to disease progression

   Author : Antonia Boman; Solbritt Rantapää-Dahlqvist; Ewa Berglin; Gerd-Marie Alenius; Mikael Brink; Heidi Kokkonen; Inger Gjertsson; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Early rheumatoid arthritis; biomarker; ACPA; RANKL; disease activity; radiological destruction; cardiovascular events; hormonal factors; reumatologi; rheumatology;

   Abstract : Rheumatoid arthritis (RA) is a chronic inflammatory joint disease, affecting approximately 0.5 to 1% of the adult population. Although the aetiology is not fully known, a complex interaction between genetic, environmental and stochastic factors is thought to trigger the pathogenic mechanisms. READ MORE

4. 2. Genetic markers in rheumatoid arthritis

   Author : Solbritt Rantapää Dahlqvist; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rheumatoid arthritis; family history; genetic marker; HLA B27; HLA DR4; properdin factor B; C3 complement; -antitrypsin; haptoglobin; transferrin;

   Abstract : Genetic as well as environmental factors are believed to be of importance in the etiology of rheumatoid arthritis (RA). There are a number of previous studies of genetic markers in RA, but so far no genetic linkage and only a few associations have been found. Of the associations only one (with the HLA antigen DR4) appears to be well documented. READ MORE

5. 3. Disease activity in rheumatoid arthritis : Studies in interleukin-6, tumour necrosis factor alpha, monocyte activity, acute phase markers, glucocorticoids, and disability

   Author : Nils Gunnar Arvidson; Anders Larsson; Arvi Larsen; Øystein Førre; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Chemistry; acute phase markers; circadian rhythm; disability; disease activity; glucocorticoids; monocyte activation; rheumatoid arthritis; Kemi; Chemistry; Kemi; Medicine; medicin;

   Abstract : In the present studies, aspects of some disease activity measures in rheumatoid arthritis (RA) have been investigated, including the effect of glucocorticoids on this activity. In RA, serum interleukin(IL)-6 levels were elevated and were shown to have a circadian rhythm, with peak levels in the morning, declining towards low or normal levels in the afternoon and evening. READ MORE

6. 4. Extra-articular Rheumatoid Arthritis Risk Factors and Consequences

   Author : Britt-Marie Nyhall-Wahlin; Malmö Institutionen för kliniska vetenskaper; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; radiographic progression; disease activity burden; smoking; rheumatoid nodules; Rheumatoid arthritis; extra-articular manifestations; TNF-inhibitor treatment;

   Abstract : Rheumatoid arthritis (RA) is a systemic disease not only restricted to the joints, but can also be associated with the development of extra-articular manifestations. Extra-articular RA (ExRA) is of clinical importance because of the associated morbidity and increased risk of premature mortality compared with RA patients in general. READ MORE

7. 5. Hormone replacement therapy in rheumatoid arthritis

   Author : Helena Forsblad d'Elia; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rheumatoid arthritis; randomised controlled trials; hormone replacement therapy; estrogen; osteoporosis; bone mineral density; bone remodelling; cartilage remodelling; cytokines; insulin-like growth factor 1;

   Abstract : Rheumatoid arthritis (RA) is 2-3 times more frequent in women as compared to men. The peak incidence in women coincides with the years around the menopause and the course of RA is also influenced by events associated with hormonal alterations. READ MORE