Search for dissertations about: "ribosome assembly"

Showing result 1 - 5 of 29 swedish dissertations containing the words ribosome assembly.

  2. 1. Nucleolar Ribosome Assembly

    Author : Fredrik Lackmann; Lars Wieslander; Denis Lafontaine; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Ribosome biogenesis; RNA; Nucleolus; Molecular Biology; molekylärbiologi;

    Abstract : Ribosomes are macromolecular machines that are responsible for production of every protein in a living cell. Yet we do not know the details about how these machines are formed. The ribosome consists of four RNA strands and roughly 80 proteins that associate with each other in the nucleolus and form pre-ribosomal complexes. READ MORE

  4. 2. Eukaryotic Ribosome Biogenesis : Focus on the function of the assembly factor Mrd1p

    Author : Åsa Segerstolpe; Lars Wieslander; Susan Gerbi; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Ribosome biogenesis; nucleolus; pre-rRNA processing; RNA-binding proteins; Mrd1; Molecular Biology; molekylärbiologi;

    Abstract : The ribosome, the protein factory of the cell, is essential for all life forms. The ribosome is a large RNA-protein machine. It is built in a complex, multi-step process that involves a large number of accessory trans-acting factors and the synthesis consumes a considerable part of the cellular energy. READ MORE

  5. 3. Translational termination, frameshift and ribosome assembly

    Author : Monica Rydén Aulin; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : The aim of this thesis was to study components involved in translational termination. Most of the work is centered around this, but the outcome of some of the experiments, led me onto other paths too.Firstly, isolation of a mutant which was shown to be in release factor one, was mapped to min 26,5 on the Escherichia coli chromosome. READ MORE

  6. 4. On the Origin and Evolution of the Mitochondrial Ribosome

    Author : Victor Tobiasson; Alexey Amunts; Loren Williams; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Ribosome; mitochondria; evolution; structural biology; biokemi; Biochemistry;

    Abstract : The ribosome is among the most ancient, intricate and well studied macromolecular complexes in biology. Predating the earliest divergence of life, its core molecular structure has remained mostly unchanged for more than three billion years. READ MORE

  7. 5. The importance of maturation factors in 30S ribosomal subunit assembly

    Author : Stefan Nord; Mikael Wikström; Dan Andersson; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Ribosome; 30S; rRNA; RimP; RbfA; C23U; rpsE; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Abstract : The assembly of the ribosome is a complex process that needs to be highly efficient to support maximum growth. Although the individual subunits of the ribosome can be reconstituted in vitro, such a reaction is inefficient in comparison to the assembly rate in vivo. READ MORE