Search for dissertations about: "rupture of membranes"

Showing result 1 - 5 of 37 swedish dissertations containing the words rupture of membranes.

  1. 1. Interaction Between Antimicrobial Peptides and Phospholipid Membranes : Effects of Peptide Length and Composition

    Author : Lovisa Ringstad; Martin Malmsten; Per Hansson; Jeremy Ramsden; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adsorption; antibacterial; antimicrobial peptide; bilayer; ellipsometry; electrochemistry; electrostatic interactions; hydrophobicity; liposome; membrane; monolayer; phospholipid; secondary structure; supported bilayer.; PHARMACY; FARMACI; Pharmaceutical Physical Chemistry; farmaceutisk fysikalisk kemi;

    Abstract : Due to increasing problems with bacterial resistance development, there is a growing need for identifying new types of antibiotics. Antimicrobial peptides constitute an interesting group of substances for this purpose, since they are believed to act mainly by disrupting the bacterial membrane, which is a fast and non-specific mechanism. READ MORE

  2. 2. Physico-Chemical Investigations of, and Characterization of Model Membranes for, Lipid-Peptide Interactions

    Author : Per Wessman; Katarina Edwards; Martin Malmsten; Michel Lafleur; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Physical chemistry; Fysikalisk kemi; Physical Chemistry; fysikalisk kemi;

    Abstract : The main focus of this thesis is on the effects caused by α-helical peptides on liposome structure, the impact of cholesterol on the peptide-membrane interactions, and the effect of aggregate curvature on the peptide affinity. Results of the studies show that the membrane destabilizing effect of the cationic α-helical peptide melittin is modulated by cholesterol. READ MORE

  3. 3. Oxidative stress-related damage of retinal pigment epithelial cells : possible protective properties of autophagocytosed iron-binding proteins

    Author : Markus Karlsson; Christina Frennesson; Sven Erik Nilsson; Tino Kurz; Ulf Brunk; Anders Kvanta; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Oxidative stress is a major pathogenic factor in the development of age-related macular degeneration (AMD), which is the most common cause of severe central visual impairment in the elderly population in the western world.It is believed that the degenerative process starts in the retinal pigment epithelium (RPE). READ MORE

  4. 4. Cervical and intra-amniotic markers of preterm birth and infection

    Author : Rose-Marie Holst; Göteborgs universitet; []
    Keywords : spontaneous preterm delivery; intra-amnioti infection inflammation; preterm labor; inflammatory proteins; preterm prelabor rupture of membranes; histological chorioamnionitis; cervical and amniotic markers;

    Abstract : Abstract Background: Preterm delivery (PTD; < 37 gestational weeks), is one of the greatest unsolved obstetrical problems worldwide. As much as 80% of the perinatal mortality and 50% of the long-term neurological handicaps are associated with PTD. Spontaneous preterm birth (SPTD), i.e. READ MORE

  5. 5. Ultrasound as predictor of perinatal outcome

    Author : Gisela Ghosh; gynekologisk och prenatal ultraljudsdiagnostik Obstetrisk; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Doppler; Ultrasound; fetus; amniotic fluid index; nuchal cord; uterine artery; umbilical vein; fetal growth restriction; umbilical artery; pulsation; pregnancy;

    Abstract : The aim of the work described in this thesis was to evaluate the value of ultrasound examinations of the amniotic fluid, umbilical cord and blood flow velocity waveform of the fetal and placental vessels as predictors of the perinatal outcome. In the first study, the amniotic fluid index (AFI) measured on admission to the labour ward was evaluated in low-risk pregnancies. READ MORE