Search for dissertations about: "secretagogin"

Found 4 swedish dissertations containing the word secretagogin.

  2. 1. Exploring the interactome of EF-hand proteins

    Author : Mikael Bauer; Biofysikalisk kemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; EF-hand; calcium; STIM; stromal interaction molecule; secretagogin; Calmodulin; calbindin D28k; protein-protein interactions; zinc; protein array;

    Abstract : EF-hand proteins are central in many cellular processes being the main group of Ca2+-sensing and buffering proteins in the cell. In the work presented in this thesis we study ligand interactions of three EF-hand proteins; calmodulin, calbindin D28k and secretagogin. READ MORE

  4. 2. Unravelling protein stability and aggregation

    Author : Tanja Weiffert; NanoLund: Centre for Nanoscience; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; protein stability; protein aggregation; amyloid beta peptide; protein stabilization; split GFP; monellin; secretagogin; ; aggregation kinetics; toxicity; aggregation mechanism; coaggregation;

    Abstract : Proteins are complex macromolecules that are fundamental to all living species. The stability of proteins are governed by non-covalent forces within the protein and between the protein and its surrounding environment. READ MORE

  5. 3. Calcium-binding proteins as markers and functional determinants of neurons in pain networks

    Author : Mingdong Zhang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The thesis focuses on the anatomical and cellular distribution of three EF-hand calcium binding proteins, secretagogin, neuronal calcium-binding protein 1 (NECAB1) and NECAB2 in dorsal root ganglia (DRGs) and spinal cord of three species, mouse, rat and human, and their possible roles in pathophysiological pain. In Paper I and Paper IV, we report that the expression of secretagogin is limited to a small subpopulation of peptidergic neurons in mouse and human DRGs expressing calcitonin generelated peptide (CGRP). READ MORE

  6. 4. Neuromodulation shapes interneuron communication in the mouse striatum

    Author : Matthijs Constantijn Dorst; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : A proper understanding of cognition relies on detailed knowledge about the functional connectivity within and between brain areas. The striatum is generally regarded as the input structure to the basal ganglia, a group of subcortical nuclei that have been demonstrated to be involved in motor function and reward, amongst other functions. READ MORE