Search for dissertations about: "secretion system"

Showing result 1 - 5 of 403 swedish dissertations containing the words secretion system.

  1. 1. Coordinating type III secretion system biogenesis in Yersinia pseudotuberculosis

    Author : Jyoti Mohan Gurung; Matthew S Francis; Maria Fällman; Dirk Linke; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Yersinia pseudotuberculosis; type III secretion system; YscX; YscY; YopN; TyeA; secretion signal; N-terminal region; site-directed mutagenesis; molekylärbiologi; Molecular Biology; mikrobiologi; Microbiology;

    Abstract : Various Gram-negative bacteria utilize type III secretion system (T3SS) to deliver effectors into eukaryotic host cells and establish mutualistic or pathogenic interactions. An example is the Ysc-Yop T3SS of pathogenic Yersinia species. READ MORE

  2. 2. The Duodenal Mucosal Bicarbonate Secretion : Role of Melatonin in Neurohumoral Control and Cellular Signaling

    Author : Markus Sjöblom; Gunnar Flemström; Olof Nylander; Karl EO Åkerman; Per M. Hellström; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology; alkaline secretion; central nervous system; duodenal enterocyte; duodenal ulcer; duodenum; enterochromaffin cell; human; intraarterial; intracellular calcium; intracerebroventricular; melatonin; rat; vagal nerve; Fysiologi; Physiology; Fysiologi;

    Abstract : The duodenal lumen is exposed to aggressive factors with a high potential to cause damage to the mucosa. Bicarbonate secretion by the duodenal mucosa is accepted as the primary important defense mechanism against the hydrochloric acid intermittently expelled from the stomach. READ MORE

  3. 3. Multiple functions of YopN in the Yersinia pseudotuberculosis type III secretion system : from regulation to in vivo infection

    Author : Sarp Bamyaci; Åke Forsberg; Edouard Galyov; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Type III secretion system; Yersinia; YopN; virulence; phagocytosis; mouse infection; secretion kinetics;

    Abstract : The type 3 secretion systems (T3SSs) are virulence mechanisms used by various Gram-negative bacteria to overcome the host immunity. They are often target-cell contact induced and activated. Activation results in targeting of virulence effector substrates into host cells. READ MORE

  4. 4. Effects of Orexins, Guanylins and Feeding on Duodenal Bicarbonate Secretion and Enterocyte Intracellular Signaling

    Author : Magnus Wilhelm Bengtsson; Gunnar Flemström; Olof Nylander; Karl E. O. Åkerman; Per M. Hellström; Uppsala universitet; []
    Keywords : Physiology; alkaline secretion; carbohydrates; central nervous system; cholinergic stimulation; duodenum; enteric nervous system; enterochromaffin cell; fasting; feeding; glucose; guanylyl cyclase C; humans; hypocretin; intra-arterial; in situ; intracerebroventricular; luminal acid; luzindole; orexin-B; SB-334867; Fysiologi;

    Abstract : The duodenal epithelium secretes bicarbonate ions and this is regarded as the primary defence mechanism against the acid discharged from the stomach. For an efficient protection, the duodenum must also function as a sensory organ identifying luminal factors. READ MORE

  5. 5. The enteric nervous sytem and infectious diarrhoea. An experimental study in mouse and rat

    Author : Shirin Kordasti; Göteborgs universitet; []
    Keywords : rotavirus; cholera; secretion; potential difference; enteric nervous system;

    Abstract : Aim: To evaluate the role of the enteric nervous system in one of the most common types of infectious diarrhoea worldwide, rotavirus infection, and to further clarify the mechanisms behind neurally mediated intestinal secretion. Methods: The experiments were performed on neonatal and adult mice and adult rats. Experimental setups: In vitro: 1. READ MORE