Search for dissertations about: "sedative"

Showing result 1 - 5 of 34 swedish dissertations containing the word sedative.

  2. 1. Sedative or hypnotic drug dependence : personality and neuropsychological characteristics

    Author : Lena Holm; Stockholms universitet; []
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Personlighetspsykologi; Droger; Test. Rorschach; Neuropsykologi;

    Abstract : .... READ MORE

  4. 2. Pharmacokinetics of the enantiomers of thalidomide

    Author : Tommy Eriksson; Avdelningen för klinisk kemi och farmakologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; protein binding; blood distribution; stereoselective pharamacokinetics; pharmacokinetic modelling; oral administration; intravenous administration; chiral inversion; stereospecific assay; HPLC; Thalidomide; hydroxylated metabolites; enantiomers; in vitro kinetics; sedative effects; concentration-effect relationship.; Pharmacological sciences; pharmacognosy; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi;

    Abstract : Thalidomide has a chiral center and the racemate of (+)-(R) and (-)-(S)-thalidomide was introduced as a hypnotic/sedative drug in 1957. In 1961 it was withdrawn due to teratogenicity and neuropathy. There is a growing interest in thalidomide treatment of immunomodulatory diseases. READ MORE

  5. 3. Use and misuse of sedative drugs and related substances - Findings in the general population and in individuals with opioid dependence

    Author : Tove Abrahamsson; Lund Psykiatri; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Substance use; Sedatives; Anxiolytics; Hypnotics; Prescription drug miuse; Benzodiazepines; Z-drugs; Pregabalin; Self-assessed health; Quality of life; Opioid dependence; Opiate maintenance treatment; Mortality;

    Abstract : Background: Prescription sedatives are efficient in the treatment of anxiety and sleeping disorders, but are associated with a risk of misuse and dependence, as well as an increased risk of accidents, injuries and overdoses, both in the general population and especially in individuals with other substance misuse. The present thesis aims to investigate prescription sedative use and misuse in two kinds of samples - in the general population, with focus on its association with subjective health and quality life, and in the subpopulation of individuals with opioid dependence, with focus on treatment outcome in opioid maintenance treatment and mortality. READ MORE

  6. 4. Inhaled sedation with isoflurane in the intensive care unit

    Author : Peter V Sackey; Karolinska Institutet; Karolinska Institutet; []
    Keywords : vaporizer; ACD; AnaConDa®; BIS; follow-up;

    Abstract : Patients in the Intensive Care Unit (ICU) may experience distress and pain, for which they are often prescribed sedative and analgesic drugs, sometimes at the cost of clinically significant side effects, such as prolonged wake-up time, drug or solvent toxicity and withdrawal. The search for the ideal sedation regimen for these patients in ongoing. READ MORE

  7. 5. Trauma - logistics and stress response

    Author : Camilla Brorsson; Silvana Naredi; Anders Sylvan; Per Dahlqvist; Mikael Bodelsson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; traumatic brain injury; multiple trauma; hydrocortisone; adrenal insufficiency; hypnotics and sedatives; citric acid; glycerol; saliva; liver; colorectal surgery;

    Abstract : Background: Trauma is a major cause of death and disability. Adverse events, such as prolonged prehospital time, hypoxia, hypotension and/or hyperventilation have been reported to correlate to poor outcome.Adequate cortisol levels are essential for survival after major trauma. READ MORE