Search for dissertations about: "seizure frequency"

Showing result 21 - 25 of 37 swedish dissertations containing the words seizure frequency.

  2. 21. Pharmacodynamics of low-dose clonazepam in children with epilepsy or spasticity : neurophysiological and clinical studies

    Author : Maria Dahlin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Children; epilepsy; spasticity; AED; clonazepam; seizures; electroencephalography; magnetoencephalography; dynamometer;

    Abstract : In children with epilepsy the evaluation of the efficacy of an antiepileptic drug (AED) is usually made by recording the seizure frequency. Some seizures are subtle and difficult to detect and epileptiform activity even without clinical seizures may cause cognitive dysfunctions. READ MORE

  4. 22. Enhancing neuronal inhibition by cell and gene therapy as a novel treatment for Epilepsy

    Author : Ana Gonzalez Ramos; Epilepsicentrum; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epilepsy; Interneurons; GABA; Human pluripotent stem cells; Cell therapy; Gene therapy; Chemogenetics; Hippocampus; TLE; Cntnap2;

    Abstract : Epilepsy is a family of heterogeneous and multifactorial neurological disorders, unified by the occurrence of spontaneous recurrent seizures. Overall, it affects 50 million people worldwide of all ages and genders. READ MORE

  5. 23. Autonomic cardiac control in patients with epilepsy : spectral analysis of heart rate variability

    Author : Håkan Persson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : SUDEP; autonomic nervous system; heart rate variability; epilepsy; carbamazepine; epilepsy surgery;

    Abstract : The heart is affected by the central nervous system via sympathetic and para-sympathetic efferents from autonomic centres in the brain stem. By assessing the beat to beat variation of the RR-intervals of the heart, i.e. the heart rate variability (HRV) it is possible to separately analyse sympathetic and parasympathetic effects on the heart. READ MORE

  6. 24. On mapping epilepsy : magneto- and electroencephalographic characterizations of epileptic activities

    Author : Karin Westin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Epilepsy is one of the most common neurological disorder, affecting up to 10 individuals per 1000 persons. The disorder have been known for several thousand years, with the first clinical descriptions dating back to ancient times. Nonetheless, characterization of the dynamics underlying epilepsy remains largely unknown. READ MORE

  7. 25. Endogenous modulators of hyperexcitability in epilepsy: electrophysiological and optogenetic delineation of neuropeptide Y mechanisms in interneurons

    Author : Marco Ledri; Lund Neurologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; interneurons; Epilepsy; Neuropeptide Y; synaptic transmission; synaptic plasticity; electrophysiology; optogenetics;

    Abstract : Epilepsy is one of the most common neurological disorders worldwide, affecting 1% of the general population, and is characterized by a predisposition for the generation of epileptic seizures. Despite having several different aetiologies, a common underlying cause of epilepsy seems to be an acquired imbalance between excitatory and inhibitory circuits in the brain, which leads to hyperexcitability and appearance of seizures. READ MORE