Search for dissertations about: "sensitive assay"
Showing result 1 - 5 of 256 swedish dissertations containing the words sensitive assay.
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1. Proximity Extension Assay : a universal tool for proteomics in precision medicine
Abstract : Precision medicine aims to utilise biomarkers to ensure the right treatment is given to the right patient at the right time. In pursuit of this goal, sensitive protein detection is essential to improve opportunities for discovery, verification, validation and development of valuable protein biomarkers. READ MORE
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2. Proximity Ligation and Barcoding Assays : Tools for analysis of proteins and protein complexes
Abstract : Proteins are fundamental structural, enzymatic and regulatory components of cells. Analysis of proteins, such as by measuring their concentrations, characterizing their modifications, and detecting their interactions, provides insights in how biological systems work physiologically or pathologically at the molecular level. READ MORE
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3. Sensitive Forensic DNA Analysis : Application of Pyrosequencing and Real-time PCR Quantification
Abstract : The field of forensic genetics is growing fast and the development and optimisation of more sensitive, faster and more discriminating forensic DNA analysis methods is highly important. In this thesis, an evaluation of the use of novel DNA technologies and the development of specific applications for use in forensic casework investigations are presented. READ MORE
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4. Testosterone and 17beta-oestradiol secretions in children and adolescents. Assay development, levels for comparison and clinical applications
Abstract : Accurate measurements of 17beta-oestradiol and testosterone are important in clinical settings of pubertal disorders and hormone replacement therapy among children. Most assays for measurement of these steroids are optimised for fertility investigations in adults and are not sensitive enough for quantification in children. READ MORE
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5. Development of sensitive cellular assay systems and their application to the identification of "orphan" seven-transmembrane receptors
Abstract : Seven-transmembrane, G-protein coupled receptors play a central role in physiology since they facilitate cell communication in multicellular organisms by recognition of a broad range of ligands. They also represent important drug targets. READ MORE