Search for dissertations about: "sequencing"

Showing result 1 - 5 of 483 swedish dissertations containing the word sequencing.

  1. 1. On Transcriptome Sequencing

    University dissertation from Stockholm : KTH

    Author : Daniel Klevebring; KTH.; [2009]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Transcriptome; RNA-seq; DNA sequencing; gene expression profiling; non-coding RNA; small RNA; NATURAL SCIENCES Biology Other biology Functional genomics; NATURVETENSKAP Biologi Övrig biologi Funktionsgenomik; NATURAL SCIENCES Biology Other biology Bioinformatics; NATURVETENSKAP Biologi Övrig biologi Bioinformatik; NATURAL SCIENCES Biology Cell and molecular biology Genetics; NATURVETENSKAP Biologi Cell- och molekylärbiologi Genetik; NATURAL SCIENCES Biology Cell and molecular biology Molecular biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Molekylärbiologi; MEDICINE Morphology; cell biology; pathology Cell biology; MEDICIN Morfologi; cellbiologi; patologi Cellbiologi;

    Abstract : This thesis is about the use of massive DNA sequencing to investigate the transcriptome. During recent decades, several studies have made it clear that the transcriptome comprises a more complex set of biochemical machinery than was previously believed. READ MORE

  2. 2. Library Preparation for High Throughput DNA Sequencing

    University dissertation from Stockholm : KTH Royal Institute of Technology

    Author : Anders Jemt; KTH.; [2017]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; DNA; RNA; sequencing; massively parallel sequencing; library preparation; automation; genome; transcriptome; Biotechnology; Bioteknologi;

    Abstract : Order 3 billion base pairs of DNA in the correct order and you get the blueprint of a human, the genome. Before the introduction of massively parallel sequencing a little more than a decade ago it would cost around $10 million to get this blueprint. READ MORE

  3. 3. Tagging systems for sequencing large cohorts

    University dissertation from Stockholm

    Author : Mårten Neiman; KTH.; KTH.; [2010]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; next generation sequencing; genotyping; massive parallel sequencing; 454; Pyrosequencing; amplicon sequencing; enrichment; DNA barcodes; NATURAL SCIENCES Biology Cell and molecular biology Genetics; NATURVETENSKAP Biologi Cell- och molekylärbiologi Genetik;

    Abstract : Advances in sequencing technologies constantly improves the throughput andaccuracy of sequencing instruments. Together with this development comes newdemands and opportunities to fully take advantage of the massive amounts of dataproduced within a sequence run. READ MORE

  4. 4. In situ Sequencing Methods for spatially-resolved transcriptome analysis

    University dissertation from Stockholm : Department of Biochemistry and Biophysics, Stockholm University

    Author : Marco Mignardi; Stockholms universitet.; [2014]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Padlock probes; rolling circle amplification; in situ sequencing; spatially-resolved transcriptomics; molecular diagnostics; biokemi; Biochemistry;

    Abstract : It is well known that cells in tissues display a large heterogeneity in gene expression due to differences in cell lineage origin and variation in the local environment at different sites in the tissue, a heterogeneity that is difficult to study by analyzing bulk RNA extracts from tissue. Recently, genome-wide transcriptome analysis technologies have enabled the analysis of this variation with single-cell resolution. READ MORE

  5. 5. Analysis of RNA and DNA sequencing data Improved bioinformatics applications

    University dissertation from Stockholm : KTH Royal Institute of Technology

    Author : Benjamín Sigurgeirsson; KTH.; [2016]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; RNA sequencing; exome sequencing; bioinformatics; gene expression; differential expression; variant calling; Biotechnology; Bioteknologi;

    Abstract : Massively parallel sequencing has rapidly revolutionized DNA and RNA research. Sample preparations are steadfastly advancing, sequencing costs have plummeted and throughput is ever growing. This progress has resulted in exponential growth in data generation with a corresponding demand for bioinformatic solutions. READ MORE