Search for dissertations about: "serological marker"

Showing result 1 - 5 of 20 swedish dissertations containing the words serological marker.

2. 1. Tissue transglutaminase autoantibodies in childhood celiac disease

   Author : Daniel Agardh; Pediatrisk endokrinologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunologi; serologi; Medicine human and vertebrates ; Medicin människa och djur ; Immunology; serology; transplantation; villous atrophy; T cells; serological marker; screening; intestinal mucosa; children; celiac disease; CD25; CD8; CD4; autoantibodies; B cells; gluten-free diet; autoimmunity;

   Abstract : Celiac disease is a prevalent small bowel disease in children caused by permanent intolerance against gliadin, which is the alcohol-soluble fraction of the cereal protein gluten in wheat, rye and barley. Celiac disease is characterized by an inflammatory infiltrate of CD4+ T lymphocytes in the intestinal mucosa leading to damage of villous structure and loss of absorptive surface. READ MORE

4. 2. Serological and faecal biomarkers in inflammatory bowel disease

   Author : Karin Amcoff; Jonas Halfvarson; Marie Carlsson; Hans Törnblom; Örebro universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Crohn s disease; ulcerative colitis; inflammatory bowel disease; faecal calprotectin; antibodies; eosinophils; ECP; EDN;

   Abstract : The inflammatory bowel diseases (IBD), Crohn's disease and ulcerative colitis, are relapsing and remitting disorders characterised by chronic inflammation at various sites in the gastrointestinal tract, resulting in diarrhoea and abdominal pain. Neither the aetiology nor the pathophysiology is yet fully understood, and there is currently no cure. READ MORE

5. 3. Human cytokeratins : their use as targets in cancer management

   Author : Birgitta Sundström; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Abstract : Cytokeratins, biochemically related to intermediate filaments (IF), form an intracellular network of filaments which contributes to the mechanical stabilizing of the cell. 19 individual polypeptides, divided into two groups, constitute the cytokeratin family. READ MORE

6. 4. Screening Detected Celiac Disease in Children

   Author : Charlotta Webb; Lund Pediatrik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Celiac disease; screening; prevalence; small-bowel biopsy; enteropathy; transglutaminase; gluten-free diet; adherence;

   Abstract : Background: The prevalence of celiac disease (CD) is estimated to be around 1%, but most CD cases are undiagnosed. Sweden experienced an epidemic of clinically detected celiac disease in children younger than 2 years of age, partly due to changes in infant feeding practices, were the amount of gluten and age at introduction was changed. READ MORE

7. 5. Type-specific human papillomavirus antibodies : detection, characterization and application in seroepidemiology

   Author : Zhaohui Wang; Karolinska Institutet; Karolinska Institutet; []
   Keywords : antagonism; antibody; capsids; cervical carcinoma; CIN; epidemiology; HPV; isotype; neutralizing epitope; PCR; STDs; trends over time; VLPs;

   Abstract : Background: Human Papillomavirus (HPV) is a sexually transmitted DNA virus that causes several human cancers, notably cervical and other anogenital cancers. The antibody response to this virus is of interest both because knowledge of the antigenic structures that induce protective immunity forms the basis for prophylactic vaccine development and because it forms the basis of seroepidemiology, the method of choice for studies of HPV infectivity, of HPV spread in populations and of cancer risks following HPV exposure. READ MORE