Search for dissertations about: "serotonergic activity"
Showing result 1 - 5 of 56 swedish dissertations containing the words serotonergic activity.
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1. Serotonergic arylcyclopropylamines : stereoselective synthesis and structure-activity relationships
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2. Serotonergic aporphine derivatives : Synthesis and structure-activity relationships
Abstract : Novel series of well-characterized and stereochemically pure 11-substituted (R)-aporphine derivatives have been prepared and their interaction with serotonin 5-HT7 and 5-HT1A receptors and dopamine D2A and D1 receptors have been studied. Efficient palladium catalyzed reactions were utilized for the diastereoselective synthesis of atropisomers as well as for the synthesis of several of the other (R)-aporphine derivatives. READ MORE
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3. Serotonergic 2-aminotetralin derivatives : synthesis and structure-activity relationships
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4. Serotonergic activity of 8-(Dialkylamino)-6,7,8,9-tetrahydro- 3H-benz[e]indole derivatives : synthesis, resolution and quantitative structure-activity relationships
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5. Imaging and Quantification of Brain Serotonergic Activity using PET
Abstract : This thesis investigates the potential of using positron emission tomography (PET) to study the biosynthesis and release of serotonin (5HT) at the brain serotonergic neuron. As PET requires probe compounds with specific attributes to enable imaging and quantification of biological processes, emphasis was placed on the evaluation of these attributes. READ MORE