Search for dissertations about: "serotype switching"

Found 4 swedish dissertations containing the words serotype switching.

  2. 1. Development of novel vaccine strains of Vibrio cholerae and studies on the role of serotype in epidemic spread of cholera

    Author : Stefan Karlsson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cholera; Vibrio cholerae; Serotype; Ogawa; Inaba; Hikojima; Vaccine; Immunogenicity; serotype switching; wbeT;

    Abstract : Cholera, caused by bacterium Vibrio cholerae O1, is a severe diarrheal disease with an estimated 3-5 million cases and more than 140 000 deaths every year particularly affecting children under 5 years of age. It can be found all over the world and often causes cholera in places where access to clean water or proper sanitary facilities are limited or compromised. READ MORE

  4. 2. Molecular epidemiology of streptococcus agalactiae : mobile elements as genetic markers

    Author : Shi-Lu Luan; Mari Norgren; Barbara Spellerberg; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Streptococcus agalactiae; group II intron GBSi1 ; multilocus sequence typing; capsular serotype; population structure; Clinical bacteriology; Klinisk bakteriologi;

    Abstract : Streptococcus agalactiae, also designated group B streptococcus (GBS), is a Gram-positive coccus, and it is an important pathogen that causes invasive disease in neonates, pregnant adults, and non-pregnant adults with predisposing conditions. The group II intron GBSi1 is one of the major mobile genetic elements identified in S. agalactiae. READ MORE

  5. 3. Mechanisms for pneumococcal meningitis and a new vaccine platform to raise a serotype-independent protection in the host

    Author : Sigrun Thorsdottir; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Streptococcus pneumoniae is a highly relevant pathogenic bacterium, responsible for a large fraction of deaths and disease morbidity in the world. The pneumococcus remains the leading cause of life-threatening pneumonia, septicemia and meningitis beyond neonatal age, despite global implementation of vaccination programs. READ MORE

  6. 4. Development of Adenoviral Vectors for Studying Hematopoietic Stem Cell Function

    Author : Marcus Järås; Institutionen för laboratoriemedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematologi; extracellulära vätskor; extracellular fluids; hTERT; adenovirus; hematopoietic stem cells; Haematology;

    Abstract : Hematopoietic stem cells (HSCs) are defined by their capacity to self-renew and differentiate into all hematopoietic cell lineages. Postnatally, HSCs reside predominantly in the bone marrow and are relatively rare, but important cells because of their therapeutic potential in bone marrow transplantation protocols and in their involvement in the origin of certain leukemias. READ MORE