Search for dissertations about: "signal peptidase"

Showing result 1 - 5 of 9 swedish dissertations containing the words signal peptidase.

  2. 1. APOLIPOPROTEIN M

    Author : Olof Axler; Malmö Klinisk kemi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; signal peptide; Apolipoprotein; signal peptidase; ELISA; MODY; coronary heart disease;

    Abstract : Apolipoprotein M (apoM) is composed of 188 amino acids and has an apparent molecular weight of 25 kDa. ApoM belongs to the lipocalin protein superfamily, and is found in all major lipoprotein classes, although the majority of apoM is found in high density lipoprotein, HDL. In apoM, the signal peptide is retained in the mature protein. READ MORE

  4. 2. Apolipoprotein M – Studies of Structure and Function

    Author : Josefin Ahnström; Malmö Klinisk kemi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; signal peptidase; signal peptide; crystallization; Apolipoprotein; lipocalin; HDL; coronary heart disease;

    Abstract : Apolipoprotein M (apoM), a 25 kDa plasma protein, is found in all major lipoprotein classes, although the majority is found in high density lipoproteins (HDL). ApoM has been suggested to be involved in the formation of and adding to the antiatherogenic functions of HDL, but its function is still not completely known. READ MORE

  5. 3. The mitochondrial processing peptidase-cytochrome bc₁ complex of S. oleracea

    Author : Sara Sjöling; Walter Neupert; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; biokemi; Biochemistry;

    Abstract : Proteins function at distinct sites within the cell, yet most of them are encoded by the nucleus and synthesised in the cytosol. Thus, newly synthesised mitochondrial proteins have to be transported within the cell. READ MORE

  6. 4. Type 2 Cystatins. Studies on the role of the major cystatin, cystatin C, in mice and on properties and distribution of the novel human cystatins F, G, H and I

    Author : Carl-Michael Nathanson; Avdelningen för klinisk kemi och farmakologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clinical chemistry; Klinisk kemi; enzyme kinetics; eosinophilic granulocytes; expression pattern; pleural effusion; knockout mouse; Cysteine peptidase; cystatin;

    Abstract : The aim the thesis work was to study the human cystatins C, E/M, F, G, H and I both in vivo and in vitro. A mouse devoid of cystatin C was used for the cystatin C studies. The levels of cystatins C, E/M and F were measured in pleural effusion samples of patients with various lung disorders. READ MORE

  7. 5. The role of TPPII in apoptosis control and treatment of malignant disease

    Author : Hong Xu; Karolinska Institutet; Karolinska Institutet; []
    Keywords : proteasome; tripeptidyl peptidase II; apoptosis; inhibitor of apoptosis LAP ; p53; Phosphoinositid-30H-kinase-related-kinases PIKK ;

    Abstract : Degradation of cytosolic proteins depends largely on the proteasome. This complex contains a catalytic core (20S) and an accessory complex (19S) that recognizes ubiquitinated substrates and translocates these to the catalytic sites in the 20S particle. READ MORE