Search for dissertations about: "single molecule imaging"
Showing result 1 - 5 of 55 swedish dissertations containing the words single molecule imaging.
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1. Single Molecule Detection : Microfluidic Automation and Digital Quantification
Abstract : Much of recent progress in medical research and diagnostics has been enabled through the advances in molecular analysis technologies, which now permit the detection and analysis of single molecules with high sensitivity and specificity. Assay sensitivity is fundamentally limited by the efficiency of the detection method used for read-out. READ MORE
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2. Probing Biomolecular Recognition at the Single Molecule Level
Abstract : Specific recognition between biomolecular partners contributes to a multitude of biochemical signaling within and between cells. The aim of this work has been to investigate the possibility to probe biomolecular recognition reactions at the smallest possible scale, the single molecule level. READ MORE
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3. Förster Resonance Energy Transfer - from single molecule spectroscopy to imaging
Abstract : During the last fifteen years several methods have been developed for probing biomolecules (DNA, RNA, proteins) one at a time. Among these methods fluorescence spectroscopy and in particular its many implementations for monitoring Förster Resonance Energy Transfer (FRET), have attracted much interest. READ MORE
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4. Advanced Fluorescence Microscopy to Study Plasma Membrane Protein Dynamics
Abstract : Membrane protein dynamics is of great importance for living organisms. The precise localization of proteins composing a synapse on the membrane facing a nerve terminus is essential for proper functioning of the nervous system. In muscle fibers, the nicotinic acetylcholine is densely packed under the motor nerve termini. READ MORE
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5. Single-molecule spectroscopy of π-conjugated polymers
Abstract : When applied to condensed-matter samples of large organic molecules, optical spectroscopy faces the problem of inhomogeneous broadening caused by the diversity of environments and conformations that sample molecules are subjected to. This severely limits the information that can be extracted from optical spectra. READ MORE