Search for dissertations about: "skin permeability"

Showing result 1 - 5 of 30 swedish dissertations containing the words skin permeability.

  2. 1. Humectants and skin : effects of hydration from molecule to man

    Author : Cathrine Albèr; Malmö högskola; []
    Keywords : skin; stratum corneum; hydration; hyaluronan; glycerol; urea;

    Abstract : Humectants belong to a group of hydrophilic compounds frequently used in skin care products with the aim to diminish the clinical symptom of skin dryness. The biochemical and biophysical mechanisms by which humectants interact with the skin barrier are far from fully understood. READ MORE

  4. 2. Sampling from a suction induced mini-erosion in human skin. Methodological studies

    Author : Christer Svedman; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vascular permeability; neurogenic inflammation; glucose; diabetes mellitus; interstitial fluid; transdermal; skin; sampling; Medicine human and vertebrates ; Medicin människa och djur ;

    Abstract : Dermal interstitial fluid (IF) was extracted serially and painlessly by brief suction for as long as 6 days. The erosion was otherwise kept occluded, Sample volumes exceded those required for measuring a wide range of biological substances. Epidermal regeneration was rapid. READ MORE

  5. 3. Non-invasive monitoring of low molecular weight biomarkers relevant to skin inflammation and cancer

    Author : Skaidre Jankovskaja; Tautgirdas Ruzgas; Johan Engblom; György Marko-Varga; Melinda Rezeli; Pawel Lukasz Urban; Malmö universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Tryptophan; Kynurenine; Phenylalanine; Tyrosine; Low molecular Weight Biomarkers; Non-Invasive; Skin Surface Sampling; Skin Permeability; Hydrogels; Prussian White; Health and society; Hälsa och samhälle;

    Abstract : Development of skin inflammation and cancer in viable epidermis and dermis involve slow molecular weight (LMW) metabolites. We hypothesize that these LMW compounds can be collected on the surface of the skin and used for non-invasive diagnostics of skin disorders. READ MORE

  6. 4. Computational modeling of biological barriers

    Author : Christian Wennberg; Erik Lindahl; Thomas Cheatham; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular dynamics; cholesterol; lipid bilayer; permeability; long-range interactions; Lennard-Jones; dispersion; particle-mesh Ewald; stratum corneum; skin formation; Biological Physics; Biologisk fysik;

    Abstract : One of the most important aspects for all life on this planet is the act to keep their biological processes in a state where they do not reach equilibrium. One part in the upholding of this imbalanced state is the barrier between the cells and their surroundings, created by the cell membrane. READ MORE

  7. 5. Skin hydration - How water and osmolytes influence biophysical properties of stratum corneum

    Author : Sebastian Björklund; Fysikalisk kemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Stratum corneum; diffusive transport; permeability; flow-through cell; Franz cell; transdermal drug delivery; water activity; vapor pressure; osmotic gradient; relative humidity; ceramide; free fatty acid; cholesterol; keratin filaments; natural moisturizing factor NMF ; urea; glycerol; molecular mobility; 13C natural-abundance solid-state NMR; polarization transfer; isothermal calorimetry; impedance spectroscopy; X-ray diffraction;

    Abstract : The outermost layer of skin (i.e., the stratum corneum, SC) is the interface that separates the water-rich inside of the body from the relatively dry external environment. SC forms an effective permeability barrier, which has to be overcome in transdermal drug delivery. READ MORE