Search for dissertations about: "solubility prediction"
Showing result 1 - 5 of 25 swedish dissertations containing the words solubility prediction.
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1. Solubility and polymorphism of molecular compounds
Abstract : This thesis deals with the controlled crystallization of small organic molecules and is focused on solubility and polymorphism. The solubility was determined for phenylacetic acid, p-hydroxyphenylacetic acid, p-aminophenylacetic acid, p-hydroxybenzoic acid and ibuprofen in both water and in a range of organic solvents. READ MORE
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2. Computational Analysis of Aqueous Drug Solubility – Influence of the Solid State
Abstract : Aqueous solubility is a key parameter influencing the bioavailability of drugs and drug candidates. In this thesis computational models for the prediction of aqueous drug solubility were explored. READ MORE
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3. Computational and Experimental Models for the Prediction of Intestinal Drug Solubility and Absorption
Abstract : New effective experimental techniques in medicinal chemistry and pharmacology have resulted in a vast increase in the number of pharmacologically interesting compounds. However, the number of new drugs undergoing clinical trial has not augmented at the same pace, which in part has been attributed to poor absorption of the compounds. READ MORE
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4. Structural, Kinetic and Thermodynamic Aspects of the Crystal Polymorphism of Substituted Monocyclic Aromatic Compounds
Abstract : This work concerns the interrelationship between thermodynamic, kinetic and structural aspects of crystal polymorphism. It is both experimental and theoretical, and limited with respect to compounds to substituted monocyclic aromatics. READ MORE
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5. Crystal Polymorphism of Substituted Monocyclic Aromatics
Abstract : .... READ MORE