Search for dissertations about: "stable isotope standard"

Showing result 1 - 5 of 14 swedish dissertations containing the words stable isotope standard.

  2. 1. Targeted proteomics methods for protein quantification of human cells, tissues and blood

    Author : Fredrik Edfors; Mathias Uhlén; Albert Heck; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; proteomics; mass spectrometry; protein quantification; stable isotope standard; parallel reaction monitoring; immuno-enrichment; Bioteknologi; Biotechnology;

    Abstract : The common concept in this thesis was to adapt and develop quantitative mass spectrometric assays focusing on reagents originating from the Human Protein Atlas project to quantify proteins in human cell lines, tissues and blood. The work is based around stable isotope labeled protein fragment standards that each represent a small part of a human protein-coding gene. READ MORE

  4. 2. High-throughput protein analysis using mass spectrometry-based methods

    Author : Tove Boström; Sophia Hober; Thomas Laurell; Ole N. Jensen; KTH; []
    Keywords : Proteomics; mass spectrometry; affinity proteomics; immunoenrichment; immunoprecipitation; IMAC; screening; protein production; protein purification; ISET; quantification; SILAC; stable isotope standard; antibody validation; Bioteknologi; Biotechnology;

    Abstract : In the field of proteomics, proteins are analyzed and quantified in high numbers. Protein analysis is of great importance and can for example generate information regarding protein function and involvement in disease. Different strategies for protein analysis and quan- tification have emerged, suitable for different applications. READ MORE

  5. 3. Fractionation of the stable silicon isotopes : analytical method developments and selected applications in geochemistry

    Author : Emma Engström; Luleå tekniska universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Applied Geology; Tillämpad geologi;

    Abstract : During the last few decades, variations in the 'natural' isotopic abundances of stable elements (termed 'fractionation') have received considerable interest from the scientific community. Though analytical methods and techniques for the measurement of isotopic abundances with adequate figures of merit have been available for light elements (e.g. READ MORE

  6. 4. Identification of brominated organic compounds in aquatic biota and exploration of bromine isotope analysis for source apportionment

    Author : Maria Unger; Örjan Gustafsson; Lillemor Asplund; Per Andersson; Sheryl Tittlemier; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Polybrominated dibenzo-p-dioxins PBDDs ; NMR spectroscopy; preparative capillary gas chromatography PCGC ; stable bromine isotope ratio; GC-multiple collector- ICP-MS; Environmental chemistry; Miljökemi; miljökemi; Environmental Chemistry;

    Abstract : Brominated organic compounds (BOCs) of both natural and anthropogenic origin are abundant in the environment. Most compounds are either clearly natural or clearly anthropogenic but some are of either mixed or uncertain origin. READ MORE

  7. 5. Stable bromine isotopic composition of methyl bromide : Method development and applications

    Author : Axel Horst; Örjan Gustafsson; Detlef Schulz-Bull; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Applied Environmental Science; tillämpad miljövetenskap;

    Abstract : The isotopic composition of ozone depleting methyl halides may provide valuable information on the sources and sinks of these compounds. However, so far mostly stable carbon isotope analysis of methyl chloride and methyl bromide (CH3Br) has been attempted. READ MORE